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Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs.
Manganelli V, Matarrese P, Antonioli M, Gambardella L, Vescovo T, Gretzmeier C, Longo A, Capozzi A, Recalchi S, Riitano G, Misasi R, Dengjel J, Malorni W, Fimia GM, Sorice M, Garofalo T. Manganelli V, et al. Among authors: gambardella l. Autophagy. 2021 Sep;17(9):2528-2548. doi: 10.1080/15548627.2020.1834207. Epub 2020 Oct 23. Autophagy. 2021. PMID: 33034545 Free PMC article.
Pyrimethamine (2,4-diamino-5-p-chlorophenyl-6-ethylpyrimidine) induces apoptosis of freshly isolated human T lymphocytes, bypassing CD95/Fas molecule but involving its intrinsic pathway.
Pierdominici M, Giammarioli AM, Gambardella L, De Felice M, Quinti I, Iacobini M, Carbonari M, Malorni W, Giovannetti A. Pierdominici M, et al. Among authors: gambardella l. J Pharmacol Exp Ther. 2005 Dec;315(3):1046-57. doi: 10.1124/jpet.105.086736. Epub 2005 Sep 12. J Pharmacol Exp Ther. 2005. PMID: 16157660
140 results