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Disturbed mitochondrial dynamics in CD8+ TILs reinforce T cell exhaustion.
Yu YR, Imrichova H, Wang H, Chao T, Xiao Z, Gao M, Rincon-Restrepo M, Franco F, Genolet R, Cheng WC, Jandus C, Coukos G, Jiang YF, Locasale JW, Zippelius A, Liu PS, Tang L, Bock C, Vannini N, Ho PC. Yu YR, et al. Among authors: ho pc. Nat Immunol. 2020 Dec;21(12):1540-1551. doi: 10.1038/s41590-020-0793-3. Epub 2020 Oct 5. Nat Immunol. 2020. PMID: 33020660
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Ho PC, Bihuniak JD, Macintyre AN, Staron M, Liu X, Amezquita R, Tsui YC, Cui G, Micevic G, Perales JC, Kleinstein SH, Abel ED, Insogna KL, Feske S, Locasale JW, Bosenberg MW, Rathmell JC, Kaech SM. Ho PC, et al. Cell. 2015 Sep 10;162(6):1217-28. doi: 10.1016/j.cell.2015.08.012. Epub 2015 Aug 27. Cell. 2015. PMID: 26321681 Free PMC article.
Regulatory circuits of T cell function in cancer.
Speiser DE, Ho PC, Verdeil G. Speiser DE, et al. Among authors: ho pc. Nat Rev Immunol. 2016 Oct;16(10):599-611. doi: 10.1038/nri.2016.80. Epub 2016 Aug 16. Nat Rev Immunol. 2016. PMID: 27526640 Review.
938 results