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In silico Design of Phl p 6 Variants With Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization.
Winter P, Stubenvoll S, Scheiblhofer S, Joubert IA, Strasser L, Briganser C, Soh WT, Hofer F, Kamenik AS, Dietrich V, Michelini S, Laimer J, Lackner P, Horejs-Hoeck J, Tollinger M, Liedl KR, Brandstetter J, Huber CG, Weiss R. Winter P, et al. Among authors: soh wt. Front Immunol. 2020 Aug 18;11:1824. doi: 10.3389/fimmu.2020.01824. eCollection 2020. Front Immunol. 2020. PMID: 33013833 Free PMC article.
Protease allergens as initiators-regulators of allergic inflammation.
Soh WT, Zhang J, Hollenberg MD, Vliagoftis H, Rothenberg ME, Sokol CL, Robinson C, Jacquet A. Soh WT, et al. Allergy. 2023 May;78(5):1148-1168. doi: 10.1111/all.15678. Epub 2023 Feb 26. Allergy. 2023. PMID: 36794967 Free PMC article. Review.
Boiling down the cysteine-stabilized LTP fold - loss of structural and immunological integrity of allergenic Art v 3 and Pru p 3 as a consequence of irreversible lanthionine formation.
Wildner S, Griessner I, Stemeseder T, Regl C, Soh WT, Stock LG, Völker T, Alessandri C, Mari A, Huber CG, Stutz H, Brandstetter H, Gadermaier G. Wildner S, et al. Among authors: soh wt. Mol Immunol. 2019 Dec;116:140-150. doi: 10.1016/j.molimm.2019.10.012. Epub 2019 Oct 22. Mol Immunol. 2019. PMID: 31654938
Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to differences in their allergenic activity.
Pablos I, Eichhorn S, Machado Y, Briza P, Neunkirchner A, Jahn-Schmid B, Wildner S, Soh WT, Ebner C, Park JW, Pickl WF, Arora N, Vieths S, Ferreira F, Gadermaier G. Pablos I, et al. Among authors: soh wt. Allergy. 2018 Feb;73(2):431-441. doi: 10.1111/all.13298. Epub 2017 Sep 27. Allergy. 2018. PMID: 28960341 Free PMC article.
27 results