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Page 1
A Novel Kv7.3 Variant in the Voltage-Sensing S4 Segment in a Family With Benign Neonatal Epilepsy: Functional Characterization and in vitro Rescue by β-Hydroxybutyrate.
Miceli F, Carotenuto L, Barrese V, Soldovieri MV, Heinzen EL, Mandel AM, Lippa N, Bier L, Goldstein DB, Cooper EC, Cilio MR, Taglialatela M, Sands TT. Miceli F, et al. Among authors: carotenuto l. Front Physiol. 2020 Sep 4;11:1040. doi: 10.3389/fphys.2020.01040. eCollection 2020. Front Physiol. 2020. PMID: 33013448 Free PMC article.
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy.
Nappi M, Barrese V, Carotenuto L, Lesca G, Labalme A, Ville D, Smol T, Rama M, Dieux-Coeslier A, Rivier-Ringenbach C, Soldovieri MV, Ambrosino P, Mosca I, Pusch M, Miceli F, Taglialatela M. Nappi M, et al. Among authors: carotenuto l. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2116887119. doi: 10.1073/pnas.2116887119. Epub 2022 Apr 4. Proc Natl Acad Sci U S A. 2022. PMID: 35377796 Free PMC article.
KCNQ2 R144 variants cause neurodevelopmental disability with language impairment and autistic features without neonatal seizures through a gain-of-function mechanism.
Miceli F, Millevert C, Soldovieri MV, Mosca I, Ambrosino P, Carotenuto L, Schrader D, Lee HK, Riviello J, Hong W, Risen S, Emrick L, Amin H, Ville D, Edery P, de Bellescize J, Michaud V, Van-Gils J, Goizet C, Willemsen MH, Kleefstra T, Møller RS, Bayat A, Devinsky O, Sands T, Korenke GC, Kluger G, Mefford HC, Brilstra E, Lesca G, Milh M, Cooper EC, Taglialatela M, Weckhuysen S. Miceli F, et al. Among authors: carotenuto l. EBioMedicine. 2022 Jul;81:104130. doi: 10.1016/j.ebiom.2022.104130. Epub 2022 Jun 30. EBioMedicine. 2022. PMID: 35780567 Free PMC article.
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity.
Musella S, Carotenuto L, Iraci N, Baroli G, Ciaglia T, Nappi P, Basilicata MG, Salviati E, Barrese V, Vestuto V, Pignataro G, Pepe G, Sommella E, Di Sarno V, Manfra M, Campiglia P, Gomez-Monterrey I, Bertamino A, Taglialatela M, Ostacolo C, Miceli F. Musella S, et al. Among authors: carotenuto l. J Med Chem. 2022 Aug 25;65(16):11340-11364. doi: 10.1021/acs.jmedchem.2c00911. Epub 2022 Aug 16. J Med Chem. 2022. PMID: 35972998 Free PMC article.
Kv7 channel activation reduces brain endothelial cell permeability and prevents kainic acid-induced blood-brain barrier damage.
Celentano C, Carotenuto L, Miceli F, Carleo G, Corrado B, Baroli G, Iervolino S, Vecchione R, Taglialatela M, Barrese V. Celentano C, et al. Among authors: carotenuto l. Am J Physiol Cell Physiol. 2024 Mar 1;326(3):C893-C904. doi: 10.1152/ajpcell.00709.2023. Epub 2024 Jan 29. Am J Physiol Cell Physiol. 2024. PMID: 38284124 Free PMC article.
In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel.
Iraci N, Carotenuto L, Ciaglia T, Belperio G, Di Matteo F, Mosca I, Carleo G, Giovanna Basilicata M, Ambrosino P, Turcio R, Puzo D, Pepe G, Gomez-Monterrey I, Soldovieri MV, Di Sarno V, Campiglia P, Miceli F, Bertamino A, Ostacolo C, Taglialatela M. Iraci N, et al. Among authors: carotenuto l. J Med Chem. 2024 Jun 13;67(11):9124-9149. doi: 10.1021/acs.jmedchem.4c00268. Epub 2024 May 23. J Med Chem. 2024. PMID: 38782404 Free PMC article.
AngioLab--a software tool for morphological analysis and endovascular treatment planning of intracranial aneurysms.
Larrabide I, Villa-Uriol MC, Cárdenes R, Barbarito V, Carotenuto L, Geers AJ, Morales HG, Pozo JM, Mazzeo MD, Bogunović H, Omedas P, Riccobene C, Macho JM, Frangi AF. Larrabide I, et al. Among authors: carotenuto l. Comput Methods Programs Biomed. 2012 Nov;108(2):806-19. doi: 10.1016/j.cmpb.2012.05.006. Epub 2012 Jun 28. Comput Methods Programs Biomed. 2012. PMID: 22749086
AngioLab: integrated technology for patient-specific management of intracranial aneurysms.
Villa-Uriol MC, Larrabide I, Geers AJ, Pozo J, Bogunovic H, Mazzeo M, Omedas P, Barbarito V, Carotenuto L, Riccobene C, Planes X, Martelli Y, Frangi AF. Villa-Uriol MC, et al. Among authors: carotenuto l. Annu Int Conf IEEE Eng Med Biol Soc. 2010;2010:6801-4. doi: 10.1109/IEMBS.2010.5625974. Annu Int Conf IEEE Eng Med Biol Soc. 2010. PMID: 21095844
33 results