Kleschevnikov AM - Search Results

1

Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model.

Chen XQ, Salehi A, Pearn ML, Overk C, Nguyen PD, Kleschevnikov AM, Maccecchini M, Mobley WC. Chen XQ, et al. Among authors: kleschevnikov am. Alzheimers Dement. 2021 Feb;17(2):271-292. doi: 10.1002/alz.12185. Epub 2020 Sep 25. Alzheimers Dement. 2021. PMID: 32975365 Free PMC article.

2

GABAergic hyperinnervation of dentate granule cells in the Ts65Dn mouse model of down syndrome: Exploring the role of App.

Mojabi FS, Fahimi A, Moghadam S, Moghadam S, Windy McNerneny M, Ponnusamy R, Kleschevnikov A, Mobley WC, Salehi A. Mojabi FS, et al. Hippocampus. 2016 Dec;26(12):1641-1654. doi: 10.1002/hipo.22664. Epub 2016 Oct 24. Hippocampus. 2016. PMID: 27701794

3

An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.

Belichenko PV, Madani R, Rey-Bellet L, Pihlgren M, Becker A, Plassard A, Vuillermot S, Giriens V, Nosheny RL, Kleschevnikov AM, Valletta JS, Bengtsson SK, Linke GR, Maloney MT, Hickman DT, Reis P, Granet A, Mlaki D, Lopez-Deber MP, Do L, Singhal N, Masliah E, Pearn ML, Pfeifer A, Muhs A, Mobley WC. Belichenko PV, et al. Among authors: kleschevnikov am. PLoS One. 2016 Mar 29;11(3):e0152471. doi: 10.1371/journal.pone.0152471. eCollection 2016. PLoS One. 2016. PMID: 27023444 Free PMC article.

4

Down syndrome.

Rafii MS, Kleschevnikov AM, Sawa M, Mobley WC. Rafii MS, et al. Among authors: kleschevnikov am. Handb Clin Neurol. 2019;167:321-336. doi: 10.1016/B978-0-12-804766-8.00017-0. Handb Clin Neurol. 2019. PMID: 31753140 Review.

5

Discoveries in Down syndrome: moving basic science to clinical care.

Kleschevnikov AM, Belichenko PV, Salehi A, Wu C. Kleschevnikov AM, et al. Prog Brain Res. 2012;197:199-221. doi: 10.1016/B978-0-444-54299-1.00010-8. Prog Brain Res. 2012. PMID: 22541294 Review.

6

Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer.

Faizi M, Bader PL, Tun C, Encarnacion A, Kleschevnikov A, Belichenko P, Saw N, Priestley M, Tsien RW, Mobley WC, Shamloo M. Faizi M, et al. Neurobiol Dis. 2011 Aug;43(2):397-413. doi: 10.1016/j.nbd.2011.04.011. Epub 2011 Apr 17. Neurobiol Dis. 2011. PMID: 21527343 Free PMC article.

7

Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome.

Salehi A, Faizi M, Colas D, Valletta J, Laguna J, Takimoto-Kimura R, Kleschevnikov A, Wagner SL, Aisen P, Shamloo M, Mobley WC. Salehi A, et al. Sci Transl Med. 2009 Nov 18;1(7):7ra17. doi: 10.1126/scitranslmed.3000258. Sci Transl Med. 2009. PMID: 20368182

8

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

Kleschevnikov AM, Belichenko PV, Villar AJ, Epstein CJ, Malenka RC, Mobley WC. Kleschevnikov AM, et al. J Neurosci. 2004 Sep 15;24(37):8153-60. doi: 10.1523/JNEUROSCI.1766-04.2004. J Neurosci. 2004. PMID: 15371516 Free PMC article.

9

Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome.

Belichenko PV, Masliah E, Kleschevnikov AM, Villar AJ, Epstein CJ, Salehi A, Mobley WC. Belichenko PV, et al. Among authors: kleschevnikov am. J Comp Neurol. 2004 Dec 13;480(3):281-98. doi: 10.1002/cne.20337. J Comp Neurol. 2004. PMID: 15515178

10

Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, Lamb BT, Epstein CJ, Stokin GB, Goldstein LS, Mobley WC. Salehi A, et al. Among authors: kleschevnikov am. Neuron. 2006 Jul 6;51(1):29-42. doi: 10.1016/j.neuron.2006.05.022. Neuron. 2006. PMID: 16815330 Free article.

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