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Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells.
Keller AN, Eckle SB, Xu W, Liu L, Hughes VA, Mak JY, Meehan BS, Pediongco T, Birkinshaw RW, Chen Z, Wang H, D'Souza C, Kjer-Nielsen L, Gherardin NA, Godfrey DI, Kostenko L, Corbett AJ, Purcell AW, Fairlie DP, McCluskey J, Rossjohn J. Keller AN, et al. Among authors: wang h. Nat Immunol. 2017 Apr;18(4):402-411. doi: 10.1038/ni.3679. Epub 2017 Feb 6. Nat Immunol. 2017. PMID: 28166217
Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection.
D'Souza C, Pediongco T, Wang H, Scheerlinck JY, Kostenko L, Esterbauer R, Stent AW, Eckle SBG, Meehan BS, Strugnell RA, Cao H, Liu L, Mak JYW, Lovrecz G, Lu L, Fairlie DP, Rossjohn J, McCluskey J, Every AL, Chen Z, Corbett AJ. D'Souza C, et al. Among authors: wang h. J Immunol. 2018 Mar 1;200(5):1901-1916. doi: 10.4049/jimmunol.1701512. Epub 2018 Jan 29. J Immunol. 2018. PMID: 29378910
MAIT cells protect against pulmonary Legionella longbeachae infection.
Wang H, D'Souza C, Lim XY, Kostenko L, Pediongco TJ, Eckle SBG, Meehan BS, Shi M, Wang N, Li S, Liu L, Mak JYW, Fairlie DP, Iwakura Y, Gunnersen JM, Stent AW, Godfrey DI, Rossjohn J, Westall GP, Kjer-Nielsen L, Strugnell RA, McCluskey J, Corbett AJ, Hinks TSC, Chen Z. Wang H, et al. Among authors: wang n. Nat Commun. 2018 Aug 22;9(1):3350. doi: 10.1038/s41467-018-05202-8. Nat Commun. 2018. PMID: 30135490 Free PMC article.
MAIT cells contribute to protection against lethal influenza infection in vivo.
van Wilgenburg B, Loh L, Chen Z, Pediongco TJ, Wang H, Shi M, Zhao Z, Koutsakos M, Nüssing S, Sant S, Wang Z, D'Souza C, Jia X, Almeida CF, Kostenko L, Eckle SBG, Meehan BS, Kallies A, Godfrey DI, Reading PC, Corbett AJ, McCluskey J, Klenerman P, Kedzierska K, Hinks TSC. van Wilgenburg B, et al. Among authors: wang h, wang z. Nat Commun. 2018 Nov 9;9(1):4706. doi: 10.1038/s41467-018-07207-9. Nat Commun. 2018. PMID: 30413689 Free PMC article.
IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection.
Wang H, Kjer-Nielsen L, Shi M, D'Souza C, Pediongco TJ, Cao H, Kostenko L, Lim XY, Eckle SBG, Meehan BS, Zhu T, Wang B, Zhao Z, Mak JYW, Fairlie DP, Teng MWL, Rossjohn J, Yu D, de St Groth BF, Lovrecz G, Lu L, McCluskey J, Strugnell RA, Corbett AJ, Chen Z. Wang H, et al. Among authors: wang b. Sci Immunol. 2019 Nov 15;4(41):eaaw0402. doi: 10.1126/sciimmunol.aaw0402. Sci Immunol. 2019. PMID: 31732518
Characterization and Purification of Mouse Mucosal-Associated Invariant T (MAIT) Cells.
Chen Z, Wang H, D'Souza C, Koay HF, Meehan B, Zhao Z, Pediongco T, Shi M, Zhu T, Wang B, Kjer-Nielsen L, Eckle SBG, Rossjohn J, Fairlie DP, Godfrey DI, Strugnell RA, McCluskey J, Corbett AJ. Chen Z, et al. Among authors: wang h, wang b. Curr Protoc Immunol. 2019 Dec;127(1):e89. doi: 10.1002/cpim.89. Curr Protoc Immunol. 2019. PMID: 31763782
Study of MAIT Cell Activation in Viral Infections In Vivo.
Hinks TSC, van Wilgenburg B, Wang H, Loh L, Koutsakos M, Kedzierska K, Corbett AJ, Chen Z. Hinks TSC, et al. Among authors: wang h. Methods Mol Biol. 2020;2098:261-281. doi: 10.1007/978-1-0716-0207-2_17. Methods Mol Biol. 2020. PMID: 31792828
Mouse models illuminate MAIT cell biology.
Wang H, Chen Z, McCluskey J, Corbett AJ. Wang H, et al. Mol Immunol. 2021 Feb;130:55-63. doi: 10.1016/j.molimm.2020.12.007. Epub 2020 Dec 22. Mol Immunol. 2021. PMID: 33360377 Free PMC article. Review.
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