Harrington L - Search Results

1

Re-equilibration of imbalanced NAD metabolism ameliorates the impact of telomere dysfunction.

Sun C, Wang K, Stock AJ, Gong Y, Demarest TG, Yang B, Giri N, Harrington L, Alter BP, Savage SA, Bohr VA, Liu Y. Sun C, et al. Among authors: harrington l. EMBO J. 2020 Nov 2;39(21):e103420. doi: 10.15252/embj.2019103420. Epub 2020 Sep 16. EMBO J. 2020. PMID: 32935380 Free PMC article.

2

Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice.

Erdmann N, Liu Y, Harrington L. Erdmann N, et al. Among authors: harrington l. Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):6080-5. doi: 10.1073/pnas.0401580101. Epub 2004 Apr 12. Proc Natl Acad Sci U S A. 2004. PMID: 15079066 Free PMC article.

3

Vault poly(ADP-ribose) polymerase is associated with mammalian telomerase and is dispensable for telomerase function and vault structure in vivo.

Liu Y, Snow BE, Kickhoefer VA, Erdmann N, Zhou W, Wakeham A, Gomez M, Rome LH, Harrington L. Liu Y, et al. Among authors: harrington l. Mol Cell Biol. 2004 Jun;24(12):5314-23. doi: 10.1128/MCB.24.12.5314-5323.2004. Mol Cell Biol. 2004. PMID: 15169895 Free PMC article.

4

Defective repair of uracil causes telomere defects in mouse hematopoietic cells.

Vallabhaneni H, Zhou F, Maul RW, Sarkar J, Yin J, Lei M, Harrington L, Gearhart PJ, Liu Y. Vallabhaneni H, et al. Among authors: harrington l. J Biol Chem. 2015 Feb 27;290(9):5502-11. doi: 10.1074/jbc.M114.607101. Epub 2015 Jan 8. J Biol Chem. 2015. PMID: 25572391 Free PMC article.

5

Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment.

Criqui M, Qamra A, Chu TW, Sharma M, Tsao J, Henry DA, Barsyte-Lovejoy D, Arrowsmith CH, Winegarden N, Lupien M, Harrington L. Criqui M, et al. Among authors: harrington l. Elife. 2020 Apr 16;9:e47333. doi: 10.7554/eLife.47333. Elife. 2020. PMID: 32297856 Free PMC article.

6

Aberrant expression and localization of the RAP1 shelterin protein contribute to age-related phenotypes.

Stock AJ, McDevitt RA, Puligilla C, Wang Y, Zhang Y, Wang K, Sun C, Becker KG, Lehrmann E, Wood WH 3rd, Gong Y, Aqdas M, Sung MH, Hoffmann V, Liu C, Gorospe M, Harrington L, Ferrucci L, Liu Y. Stock AJ, et al. Among authors: harrington l. PLoS Genet. 2022 Nov 28;18(11):e1010506. doi: 10.1371/journal.pgen.1010506. eCollection 2022 Nov. PLoS Genet. 2022. PMID: 36441670 Free PMC article.

7

The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo.

Liu Y, Snow BE, Hande MP, Yeung D, Erdmann NJ, Wakeham A, Itie A, Siderovski DP, Lansdorp PM, Robinson MO, Harrington L. Liu Y, et al. Among authors: harrington l. Curr Biol. 2000 Nov 16;10(22):1459-62. doi: 10.1016/s0960-9822(00)00805-8. Curr Biol. 2000. PMID: 11102810 Free article.

8

Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.

Liu Y, Kha H, Ungrin M, Robinson MO, Harrington L. Liu Y, et al. Among authors: harrington l. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3597-602. doi: 10.1073/pnas.062549199. Proc Natl Acad Sci U S A. 2002. PMID: 11904422 Free PMC article.

P., Lansdorp, P. M., Robinson, M. O. & Harrington, L. (2000) Curr. Biol. 10, 1459-1462]. Unexpectedly, although average telomere length in mTert(+/-) ES cells declined to a similar level as mTert-null ES cells, mTert(+/-) ES cell lines retained a minimal telomer …

P., Lansdorp, P. M., Robinson, M. O. & Harrington, L. (2000) Curr. Biol. 10, 1459-1462]. Unexpectedly, although average te …

9

Telomerase reverse transcriptase-dependent telomere equilibration mitigates tissue dysfunction in mTert heterozygotes.

Meznikova M, Erdmann N, Allsopp R, Harrington LA. Meznikova M, et al. Dis Model Mech. 2009 Nov-Dec;2(11-12):620-6. doi: 10.1242/dmm.004069. Epub 2009 Oct 19. Dis Model Mech. 2009. PMID: 19841238 Free PMC article.

10

Haploinsufficiency and telomere length homeostasis.

Harrington L. Harrington L. Mutat Res. 2012 Feb 1;730(1-2):37-42. doi: 10.1016/j.mrfmmm.2011.11.004. Epub 2011 Nov 7. Mutat Res. 2012. PMID: 22100521 Review.

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