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The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders.
Chen C, Meng Q, Xia Y, Ding C, Wang L, Dai R, Cheng L, Gunaratne P, Gibbs RA, Min S, Coarfa C, Reid JG, Zhang C, Jiao C, Jiang Y, Giase G, Thomas A, Fitzgerald D, Brunetti T, Shieh A, Xia C, Wang Y, Wang Y, Badner JA, Gershon ES, White KP, Liu C. Chen C, et al. Among authors: wang l, wang y. Sci Transl Med. 2018 Dec 19;10(472):eaat8178. doi: 10.1126/scitranslmed.aat8178. Epub 2018 Dec 13. Sci Transl Med. 2018. PMID: 30545964 Free PMC article.
Integrative analyses prioritize GNL3 as a risk gene for bipolar disorder.
Meng Q, Wang L, Dai R, Wang J, Ren Z, Liu S, Xia Y, Jiang Y, Duan F, Wang K, Liu C, Chen C. Meng Q, et al. Among authors: wang l, wang k, wang j. Mol Psychiatry. 2020 Nov;25(11):2672-2684. doi: 10.1038/s41380-020-00866-5. Epub 2020 Aug 21. Mol Psychiatry. 2020. PMID: 32826963
Analyses of the autism-associated neuroligin-3 R451C mutation in human neurons reveal a gain-of-function synaptic mechanism.
Wang L, Mirabella VR, Dai R, Su X, Xu R, Jadali A, Bernabucci M, Singh I, Chen Y, Tian J, Jiang P, Kwan KY, Pak C, Liu C, Comoletti D, Hart RP, Chen C, Südhof TC, Pang ZP. Wang L, et al. Mol Psychiatry. 2024 Jun;29(6):1620-1635. doi: 10.1038/s41380-022-01834-x. Epub 2022 Oct 24. Mol Psychiatry. 2024. PMID: 36280753 Free PMC article.
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