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Safety and immunogenicity of a novel hexavalent group B streptococcus conjugate vaccine in healthy, non-pregnant adults: a phase 1/2, randomised, placebo-controlled, observer-blinded, dose-escalation trial.
Absalon J, Segall N, Block SL, Center KJ, Scully IL, Giardina PC, Peterson J, Watson WJ, Gruber WC, Jansen KU, Peng Y, Munson S, Pavliakova D, Scott DA, Anderson AS. Absalon J, et al. Among authors: scully il. Lancet Infect Dis. 2021 Feb;21(2):263-274. doi: 10.1016/S1473-3099(20)30478-3. Epub 2020 Sep 3. Lancet Infect Dis. 2021. PMID: 32891191 Free PMC article. Clinical Trial.
Staphylococcus aureus manganese transport protein C is a highly conserved cell surface protein that elicits protective immunity against S. aureus and Staphylococcus epidermidis.
Anderson AS, Scully IL, Timofeyeva Y, Murphy E, McNeil LK, Mininni T, Nuñez L, Carriere M, Singer C, Dilts DA, Jansen KU. Anderson AS, et al. Among authors: scully il. J Infect Dis. 2012 Jun;205(11):1688-96. doi: 10.1093/infdis/jis272. Epub 2012 Apr 2. J Infect Dis. 2012. PMID: 22474033 Free PMC article.
A recombinant clumping factor A-containing vaccine induces functional antibodies to Staphylococcus aureus that are not observed after natural exposure.
Hawkins J, Kodali S, Matsuka YV, McNeil LK, Mininni T, Scully IL, Vernachio JH, Severina E, Girgenti D, Jansen KU, Anderson AS, Donald RG. Hawkins J, et al. Among authors: scully il. Clin Vaccine Immunol. 2012 Oct;19(10):1641-50. doi: 10.1128/CVI.00354-12. Epub 2012 Aug 15. Clin Vaccine Immunol. 2012. PMID: 22896688 Free PMC article.
44 results