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Page 1
A radioligand binding assay for the insulin-like growth factor 2 receptor.
Potalitsyn P, Selicharová I, Sršeň K, Radosavljević J, Marek A, Nováková K, Jiráček J, Žáková L. Potalitsyn P, et al. PLoS One. 2020 Sep 2;15(9):e0238393. doi: 10.1371/journal.pone.0238393. eCollection 2020. PLoS One. 2020. PMID: 32877466 Free PMC article.
Converting Insulin-like Growth Factors 1 and 2 into High-Affinity Ligands for Insulin Receptor Isoform A by the Introduction of an Evolutionarily Divergent Mutation.
Macháčková K, Chrudinová M, Radosavljević J, Potalitsyn P, Křížková K, Fábry M, Selicharová I, Collinsová M, Brzozowski AM, Žáková L, Jiráček J. Macháčková K, et al. Among authors: potalitsyn p. Biochemistry. 2018 Apr 24;57(16):2373-2382. doi: 10.1021/acs.biochem.7b01260. Epub 2018 Apr 10. Biochemistry. 2018. PMID: 29608283 Free article.
Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses.
Macháčková K, Mlčochová K, Potalitsyn P, Hanková K, Socha O, Buděšínský M, Muždalo A, Lepšík M, Černeková M, Radosavljević J, Fábry M, Mitrová K, Chrudinová M, Lin J, Yurenko Y, Hobza P, Selicharová I, Žáková L, Jiráček J. Macháčková K, et al. Among authors: potalitsyn p. J Biol Chem. 2019 Nov 15;294(46):17371-17382. doi: 10.1074/jbc.RA119.010072. Epub 2019 Sep 26. J Biol Chem. 2019. PMID: 31558604 Free PMC article.
The efficiency of insulin production and its content in insulin-expressing model β-cells correlate with their Zn2+ levels.
Dzianová P, Asai S, Chrudinová M, Kosinová L, Potalitsyn P, Šácha P, Hadravová R, Selicharová I, Kříž J, Turkenburg JP, Brzozowski AM, Jiráček J, Žáková L. Dzianová P, et al. Among authors: potalitsyn p. Open Biol. 2020 Oct;10(10):200137. doi: 10.1098/rsob.200137. Epub 2020 Oct 21. Open Biol. 2020. PMID: 33081637 Free PMC article.
Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2.
Potalitsyn P, Mrázková L, Selicharová I, Tencerová M, Ferenčáková M, Chrudinová M, Turnovská T, Brzozowski AM, Marek A, Kaminský J, Jiráček J, Žáková L. Potalitsyn P, et al. Commun Biol. 2023 Aug 19;6(1):863. doi: 10.1038/s42003-023-05239-6. Commun Biol. 2023. PMID: 37598269 Free PMC article.