Žáková L - Search Results

1

A radioligand binding assay for the insulin-like growth factor 2 receptor.

Potalitsyn P, Selicharová I, Sršeň K, Radosavljević J, Marek A, Nováková K, Jiráček J, Žáková L. Potalitsyn P, et al. Among authors: zakova l. PLoS One. 2020 Sep 2;15(9):e0238393. doi: 10.1371/journal.pone.0238393. eCollection 2020. PLoS One. 2020. PMID: 32877466 Free PMC article.

2

Shortened insulin analogues: marked changes in biological activity resulting from replacement of TyrB26 and N-methylation of peptide bonds in the C-terminus of the B-chain.

Záková L, Barth T, Jirácek J, Barthová J, Zórad S. Záková L, et al. Biochemistry. 2004 Mar 2;43(8):2323-31. doi: 10.1021/bi036001w. Biochemistry. 2004. PMID: 14979729

3

Preparation and characterization of two LysB29 specifically labelled fluorescent derivatives of human insulin.

Ciencialová A, Záková L, Jirácek J, Barthová J, Barth T. Ciencialová A, et al. Among authors: zakova l. J Pept Sci. 2004 Jul;10(7):470-8. doi: 10.1002/psc.556. J Pept Sci. 2004. PMID: 15298182

4

A new colorimetric assay for methionyl aminopeptidases: examination of the binding of a new class of pseudopeptide analog inhibitors.

Mitra S, Dygas-Holz AM, Jiracek J, Zertova M, Zakova L, Holz RC. Mitra S, et al. Among authors: zakova l. Anal Biochem. 2006 Oct 1;357(1):43-9. doi: 10.1016/j.ab.2006.06.012. Epub 2006 Jun 28. Anal Biochem. 2006. PMID: 16844071

5

The use of Fmoc-Lys(Pac)-OH and penicillin G acylase in the preparation of novel semisynthetic insulin analogs.

Záková L, Zyka D, Jezek J, Hanclová I, Sanda M, Brzozowski AM, Jirácek J. Záková L, et al. J Pept Sci. 2007 May;13(5):334-41. doi: 10.1002/psc.847. J Pept Sci. 2007. PMID: 17436342

6

Insulin analogues with modifications at position B26. Divergence of binding affinity and biological activity.

Záková L, Kazdová L, Hanclová I, Protivínská E, Sanda M, Budesínský M, Jirácek J. Záková L, et al. Biochemistry. 2008 May 27;47(21):5858-68. doi: 10.1021/bi702086w. Epub 2008 May 2. Biochemistry. 2008. PMID: 18452310

7

Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues.

Jirácek J, Záková L, Antolíková E, Watson CJ, Turkenburg JP, Dodson GG, Brzozowski AM. Jirácek J, et al. Among authors: zakova l. Proc Natl Acad Sci U S A. 2010 Feb 2;107(5):1966-70. doi: 10.1073/pnas.0911785107. Epub 2010 Jan 25. Proc Natl Acad Sci U S A. 2010. PMID: 20133841 Free PMC article.

8

Non-equivalent role of inter- and intramolecular hydrogen bonds in the insulin dimer interface.

Antolíková E, Žáková L, Turkenburg JP, Watson CJ, Hančlová I, Šanda M, Cooper A, Kraus T, Brzozowski AM, Jiráček J. Antolíková E, et al. Among authors: zakova l. J Biol Chem. 2011 Oct 21;286(42):36968-77. doi: 10.1074/jbc.M111.265249. Epub 2011 Aug 31. J Biol Chem. 2011. PMID: 21880708 Free PMC article.

9

How insulin engages its primary binding site on the insulin receptor.

Menting JG, Whittaker J, Margetts MB, Whittaker LJ, Kong GK, Smith BJ, Watson CJ, Záková L, Kletvíková E, Jiráček J, Chan SJ, Steiner DF, Dodson GG, Brzozowski AM, Weiss MA, Ward CW, Lawrence MC. Menting JG, et al. Among authors: zakova l. Nature. 2013 Jan 10;493(7431):241-5. doi: 10.1038/nature11781. Nature. 2013. PMID: 23302862 Free PMC article.

10

Structural integrity of the B24 site in human insulin is important for hormone functionality.

Žáková L, Kletvíková E, Veverka V, Lepsík M, Watson CJ, Turkenburg JP, Jirácek J, Brzozowski AM. Žáková L, et al. J Biol Chem. 2013 Apr 12;288(15):10230-40. doi: 10.1074/jbc.M112.448050. Epub 2013 Feb 27. J Biol Chem. 2013. PMID: 23447530 Free PMC article.

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