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Page 1
Inhibitors of BRAF dimers using an allosteric site.
Cotto-Rios XM, Agianian B, Gitego N, Zacharioudakis E, Giricz O, Wu Y, Zou Y, Verma A, Poulikakos PI, Gavathiotis E. Cotto-Rios XM, et al. Nat Commun. 2020 Sep 1;11(1):4370. doi: 10.1038/s41467-020-18123-2. Nat Commun. 2020. PMID: 32873792 Free PMC article.
Chemical genetics: Unraveling cell death mysteries.
Cotto-Rios XM, Gavathiotis E. Cotto-Rios XM, et al. Nat Chem Biol. 2016 Jun 17;12(7):470-1. doi: 10.1038/nchembio.2110. Nat Chem Biol. 2016. PMID: 27315536 Free PMC article.
The RUNX1/IL-34/CSF-1R axis is an autocrinally regulated modulator of resistance to BRAF-V600E inhibition in melanoma.
Giricz O, Mo Y, Dahlman KB, Cotto-Rios XM, Vardabasso C, Nguyen H, Matusow B, Bartenstein M, Polishchuk V, Johnson DB, Bhagat TD, Shellooe R, Burton E, Tsai J, Zhang C, Habets G, Greally JM, Yu Y, Kenny PA, Fields GB, Pradhan K, Stanley ER, Bernstein E, Bollag G, Gavathiotis E, West BL, Sosman JA, Verma AK. Giricz O, et al. Among authors: cotto rios xm. JCI Insight. 2018 Jul 26;3(14):e120422. doi: 10.1172/jci.insight.120422. eCollection 2018 Jul 26. JCI Insight. 2018. PMID: 30046005 Free PMC article.
Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration.
Gomez-Sintes R, Xin Q, Jimenez-Loygorri JI, McCabe M, Diaz A, Garner TP, Cotto-Rios XM, Wu Y, Dong S, Reynolds CA, Patel B, de la Villa P, Macian F, Boya P, Gavathiotis E, Cuervo AM. Gomez-Sintes R, et al. Among authors: cotto rios xm. Nat Commun. 2022 Jul 21;13(1):4220. doi: 10.1038/s41467-022-31869-1. Nat Commun. 2022. PMID: 35864098 Free PMC article.
Deubiquitinases as a signaling target of oxidative stress.
Cotto-Rios XM, Békés M, Chapman J, Ueberheide B, Huang TT. Cotto-Rios XM, et al. Cell Rep. 2012 Dec 27;2(6):1475-84. doi: 10.1016/j.celrep.2012.11.011. Epub 2012 Dec 6. Cell Rep. 2012. PMID: 23219552 Free PMC article.