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APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease.
Nguyen AT, Wang K, Hu G, Wang X, Miao Z, Azevedo JA, Suh E, Van Deerlin VM, Choi D, Roeder K, Li M, Lee EB. Nguyen AT, et al. Acta Neuropathol. 2020 Oct;140(4):477-493. doi: 10.1007/s00401-020-02200-3. Epub 2020 Aug 25. Acta Neuropathol. 2020. PMID: 32840654 Free PMC article.
Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau.
Darwich NF, Phan JM, Kim B, Suh E, Papatriantafyllou JD, Changolkar L, Nguyen AT, O'Rourke CM, He Z, Porta S, Gibbons GS, Luk KC, Papageorgiou SG, Grossman M, Massimo L, Irwin DJ, McMillan CT, Nasrallah IM, Toro C, Aguirre GK, Van Deerlin VM, Lee EB. Darwich NF, et al. Among authors: nguyen at. Science. 2020 Nov 20;370(6519):eaay8826. doi: 10.1126/science.aay8826. Epub 2020 Oct 1. Science. 2020. PMID: 33004675 Free PMC article.
Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts.
Nelson PT, Brayne C, Flanagan ME, Abner EL, Agrawal S, Attems J, Castellani RJ, Corrada MM, Cykowski MD, Di J, Dickson DW, Dugger BN, Ervin JF, Fleming J, Graff-Radford J, Grinberg LT, Hokkanen SRK, Hunter S, Kapasi A, Kawas CH, Keage HAD, Keene CD, Kero M, Knopman DS, Kouri N, Kovacs GG, Labuzan SA, Larson EB, Latimer CS, Leite REP, Matchett BJ, Matthews FE, Merrick R, Montine TJ, Murray ME, Myllykangas L, Nag S, Nelson RS, Neltner JH, Nguyen AT, Petersen RC, Polvikoski T, Reichard RR, Rodriguez RD, Suemoto CK, Wang SJ, Wharton SB, White L, Schneider JA. Nelson PT, et al. Among authors: nguyen at. Acta Neuropathol. 2022 Jul;144(1):27-44. doi: 10.1007/s00401-022-02444-1. Epub 2022 Jun 13. Acta Neuropathol. 2022. PMID: 35697880 Free PMC article.
TREM2 risk variants are associated with atypical Alzheimer's disease.
Kim B, Suh E, Nguyen AT, Prokop S, Mikytuck B, Olatunji OA, Robinson JL, Grossman M, Phillips JS, Irwin DJ, Mechanic-Hamilton D, Wolk DA, Trojanowski JQ, McMillan CT, Van Deerlin VM, Lee EB. Kim B, et al. Among authors: nguyen at. Acta Neuropathol. 2022 Dec;144(6):1085-1102. doi: 10.1007/s00401-022-02495-4. Epub 2022 Sep 16. Acta Neuropathol. 2022. PMID: 36112222 Free PMC article.
Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway.
Lin YC, Kumar MS, Ramesh N, Anderson EN, Nguyen AT, Kim B, Cheung S, McDonough JA, Skarnes WC, Lopez-Gonzalez R, Landers JE, Fawzi NL, Mackenzie IRA, Lee EB, Nickerson JA, Grunwald D, Pandey UB, Bosco DA. Lin YC, et al. Among authors: nguyen at. Nat Neurosci. 2021 Aug;24(8):1077-1088. doi: 10.1038/s41593-021-00859-9. Epub 2021 May 31. Nat Neurosci. 2021. PMID: 34059832 Free PMC article.
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination.
Ho WY, Chang JC, Lim K, Cazenave-Gassiot A, Nguyen AT, Foo JC, Muralidharan S, Viera-Ortiz A, Ong SJM, Hor JH, Agrawal I, Hoon S, Arogundade OA, Rodriguez MJ, Lim SM, Kim SH, Ravits J, Ng SY, Wenk MR, Lee EB, Tucker-Kellogg G, Ling SC. Ho WY, et al. Among authors: nguyen at. J Cell Biol. 2021 Sep 6;220(9):e201910213. doi: 10.1083/jcb.201910213. Epub 2021 Aug 4. J Cell Biol. 2021. PMID: 34347016 Free PMC article.
Microglial TREM2 in amyotrophic lateral sclerosis.
Xie M, Zhao S, Bosco DB, Nguyen A, Wu LJ. Xie M, et al. Dev Neurobiol. 2022 Jan;82(1):125-137. doi: 10.1002/dneu.22864. Epub 2021 Dec 18. Dev Neurobiol. 2022. PMID: 34874625 Free PMC article. Review.
Association of plasma biomarkers of amyloid and neurodegeneration with cerebrovascular disease and Alzheimer's disease.
Graff-Radford J, Mielke MM, Hofrenning EI, Kouri N, Lesnick TG, Moloney CM, Rabinstein A, Cabrera-Rodriguez JN, Rothberg DM, Przybelski SA, Petersen RC, Knopman DS, Dickson DW, Jack CR, Algeciras-Schimnich A, Nguyen AT, Murray ME, Vemuri P. Graff-Radford J, et al. Among authors: nguyen at. Neurobiol Aging. 2022 Nov;119:1-7. doi: 10.1016/j.neurobiolaging.2022.07.006. Epub 2022 Jul 24. Neurobiol Aging. 2022. PMID: 35952440 Free PMC article.
Neuropathologic scales of cerebrovascular disease associated with diffusion changes on MRI.
Nguyen AT, Kouri N, Labuzan SA, Przybelski SA, Lesnick TG, Raghavan S, Reid RI, Reichard RR, Knopman DS, Petersen RC, Jack CR Jr, Mielke MM, Dickson DW, Graff-Radford J, Murray ME, Vemuri P. Nguyen AT, et al. Acta Neuropathol. 2022 Dec;144(6):1117-1125. doi: 10.1007/s00401-022-02465-w. Epub 2022 Jul 16. Acta Neuropathol. 2022. PMID: 35841412 Free PMC article.
Global neuropathologic severity of Alzheimer's disease and locus coeruleus vulnerability influences plasma phosphorylated tau levels.
Murray ME, Moloney CM, Kouri N, Syrjanen JA, Matchett BJ, Rothberg DM, Tranovich JF, Sirmans TNH, Wiste HJ, Boon BDC, Nguyen AT, Reichard RR, Dickson DW, Lowe VJ, Dage JL, Petersen RC, Jack CR Jr, Knopman DS, Vemuri P, Graff-Radford J, Mielke MM. Murray ME, et al. Among authors: nguyen at. Mol Neurodegener. 2022 Dec 27;17(1):85. doi: 10.1186/s13024-022-00578-0. Mol Neurodegener. 2022. PMID: 36575455 Free PMC article.
969 results