Jobling MG - Search Results

1

Evaluation of the Immunogenicity and Protective Efficacy of an Enterotoxigenic Escherichia coli CFA/I Adhesin-Heat-Labile Toxin Chimera.

O'Dowd A, Maciel M Jr, Poole ST, Jobling MG, Rollenhagen JE, Woods CM, Sincock SA, McVeigh AL, Gregory MJ, Maves RC, Prouty MG, Holmes RK, Savarino SJ. O'Dowd A, et al. Among authors: jobling mg. Infect Immun. 2020 Oct 19;88(11):e00252-20. doi: 10.1128/IAI.00252-20. Print 2020 Oct 19. Infect Immun. 2020. PMID: 32839188 Free PMC article.

2

Mutational analysis of ganglioside GM(1)-binding ability, pentamer formation, and epitopes of cholera toxin B (CTB) subunits and CTB/heat-labile enterotoxin B subunit chimeras.

Jobling MG, Holmes RK. Jobling MG, et al. Infect Immun. 2002 Mar;70(3):1260-71. doi: 10.1128/IAI.70.3.1260-1271.2002. Infect Immun. 2002. PMID: 11854209 Free PMC article.

3

Use of translational fusion of the MrpH fimbrial adhesin-binding domain with the cholera toxin A2 domain, coexpressed with the cholera toxin B subunit, as an intranasal vaccine to prevent experimental urinary tract infection by Proteus mirabilis.

Li X, Erbe JL, Lockatell CV, Johnson DE, Jobling MG, Holmes RK, Mobley HL. Li X, et al. Among authors: jobling mg. Infect Immun. 2004 Dec;72(12):7306-10. doi: 10.1128/IAI.72.12.7306-7310.2004. Infect Immun. 2004. PMID: 15557656 Free PMC article.

4

Biochemical and immunological characterization of an ETEC CFA/I adhesin cholera toxin B subunit chimera.

Jobling MG, Poole ST, Rasulova-Lewis F, O'Dowd A, McVeigh AL, Balakrishnan A, Sincock SA, Prouty MG, Holmes RK, Savarino SJ. Jobling MG, et al. PLoS One. 2020 Mar 16;15(3):e0230138. doi: 10.1371/journal.pone.0230138. eCollection 2020. PLoS One. 2020. PMID: 32176708 Free PMC article.

5

Fusion proteins containing the A2 domain of cholera toxin assemble with B polypeptides of cholera toxin to form immunoreactive and functional holotoxin-like chimeras.

Jobling MG, Holmes RK. Jobling MG, et al. Infect Immun. 1992 Nov;60(11):4915-24. doi: 10.1128/iai.60.11.4915-4924.1992. Infect Immun. 1992. PMID: 1399002 Free PMC article.

6

Transfer of the cholera toxin A1 polypeptide from the endoplasmic reticulum to the cytosol is a rapid process facilitated by the endoplasmic reticulum-associated degradation pathway.

Teter K, Allyn RL, Jobling MG, Holmes RK. Teter K, et al. Among authors: jobling mg. Infect Immun. 2002 Nov;70(11):6166-71. doi: 10.1128/IAI.70.11.6166-6171.2002. Infect Immun. 2002. PMID: 12379694 Free PMC article.

7

Vesicular transport is not required for the cytoplasmic pool of cholera toxin to interact with the stimulatory alpha subunit of the heterotrimeric g protein.

Teter K, Jobling MG, Holmes RK. Teter K, et al. Among authors: jobling mg. Infect Immun. 2004 Dec;72(12):6826-35. doi: 10.1128/IAI.72.12.6826-6835.2004. Infect Immun. 2004. PMID: 15557603 Free PMC article.

8

The cholera toxin A1(3) subdomain is essential for interaction with ADP-ribosylation factor 6 and full toxic activity but is not required for translocation from the endoplasmic reticulum to the cytosol.

Teter K, Jobling MG, Sentz D, Holmes RK. Teter K, et al. Among authors: jobling mg. Infect Immun. 2006 Apr;74(4):2259-67. doi: 10.1128/IAI.74.4.2259-2267.2006. Infect Immun. 2006. PMID: 16552056 Free PMC article.

9

Type II heat-labile enterotoxins from 50 diverse Escherichia coli isolates belong almost exclusively to the LT-IIc family and may be prophage encoded.

Jobling MG, Holmes RK. Jobling MG, et al. PLoS One. 2012;7(1):e29898. doi: 10.1371/journal.pone.0029898. Epub 2012 Jan 5. PLoS One. 2012. PMID: 22242186 Free PMC article.

10

Initial studies of the structural signal for extracellular transport of cholera toxin and other proteins recognized by Vibrio cholerae.

Connell TD, Metzger DJ, Wang M, Jobling MG, Holmes RK. Connell TD, et al. Among authors: jobling mg. Infect Immun. 1995 Oct;63(10):4091-8. doi: 10.1128/iai.63.10.4091-4098.1995. Infect Immun. 1995. PMID: 7558324 Free PMC article.

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