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Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.
Pitrez PR, Estronca L, Monteiro LM, Colell G, Vazão H, Santinha D, Harhouri K, Thornton D, Navarro C, Egesipe AL, Carvalho T, Dos Santos RL, Lévy N, Smith JC, de Magalhães JP, Ori A, Bernardo A, De Sandre-Giovannoli A, Nissan X, Rosell A, Ferreira L. Pitrez PR, et al. Among authors: ferreira l. Nat Commun. 2020 Aug 17;11(1):4110. doi: 10.1038/s41467-020-17901-2. Nat Commun. 2020. PMID: 32807790 Free PMC article.
Drug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.
Blondel S, Egesipe AL, Picardi P, Jaskowiak AL, Notarnicola M, Ragot J, Tournois J, Le Corf A, Brinon B, Poydenot P, Georges P, Navarro C, Pitrez PR, Ferreira L, Bollot G, Bauvais C, Laustriat D, Mejat A, De Sandre-Giovannoli A, Levy N, Bifulco M, Peschanski M, Nissan X. Blondel S, et al. Among authors: ferreira l. Cell Death Dis. 2016 Feb 18;7(2):e2105. doi: 10.1038/cddis.2015.374. Cell Death Dis. 2016. PMID: 26890144 Free PMC article.
Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model.
Ribas J, Zhang YS, Pitrez PR, Leijten J, Miscuglio M, Rouwkema J, Dokmeci MR, Nissan X, Ferreira L, Khademhosseini A. Ribas J, et al. Among authors: ferreira l. Small. 2017 Apr;13(15):10.1002/smll.201603737. doi: 10.1002/smll.201603737. Epub 2017 Feb 17. Small. 2017. PMID: 28211642 Free PMC article.
High-throughput identification of small molecules that affect human embryonic vascular development.
Vazão H, Rosa S, Barata T, Costa R, Pitrez PR, Honório I, de Vries MR, Papatsenko D, Benedito R, Saris D, Khademhosseini A, Quax PH, Pereira CF, Mercader N, Fernandes H, Ferreira L. Vazão H, et al. Among authors: ferreira l. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):E3022-E3031. doi: 10.1073/pnas.1617451114. Epub 2017 Mar 27. Proc Natl Acad Sci U S A. 2017. PMID: 28348206 Free PMC article.
Restoring heart function and electrical integrity: closing the circuit.
Monteiro LM, Vasques-Nóvoa F, Ferreira L, Pinto-do-Ó P, Nascimento DS. Monteiro LM, et al. Among authors: ferreira l. NPJ Regen Med. 2017 Apr 7;2:9. doi: 10.1038/s41536-017-0015-2. eCollection 2017. NPJ Regen Med. 2017. PMID: 29302345 Free PMC article. Review.
4,574 results