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AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer.
Varga J, Nicolas A, Petrocelli V, Pesic M, Mahmoud A, Michels BE, Etlioglu E, Yepes D, Häupl B, Ziegler PK, Bankov K, Wild PJ, Wanninger S, Medyouf H, Farin HF, Tejpar S, Oellerich T, Ruland J, Siebel CW, Greten FR. Varga J, et al. Among authors: siebel cw. J Exp Med. 2020 Oct 5;217(10):e20191515. doi: 10.1084/jem.20191515. J Exp Med. 2020. PMID: 32749453 Free PMC article.
Constitutive NOTCH3 Signaling Promotes the Growth of Basal Breast Cancers.
Choy L, Hagenbeek TJ, Solon M, French D, Finkle D, Shelton A, Venook R, Brauer MJ, Siebel CW. Choy L, et al. Among authors: siebel cw. Cancer Res. 2017 Mar 15;77(6):1439-1452. doi: 10.1158/0008-5472.CAN-16-1022. Epub 2017 Jan 20. Cancer Res. 2017. PMID: 28108512
Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL.
Machuca-Parra AI, Bigger-Allen AA, Sanchez AV, Boutabla A, Cardona-Vélez J, Amarnani D, Saint-Geniez M, Siebel CW, Kim LA, D'Amore PA, Arboleda-Velasquez JF. Machuca-Parra AI, et al. Among authors: siebel cw. J Exp Med. 2017 Aug 7;214(8):2271-2282. doi: 10.1084/jem.20161715. Epub 2017 Jul 11. J Exp Med. 2017. PMID: 28698285 Free PMC article.
Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.
Franciosa G, Diluvio G, Gaudio FD, Giuli MV, Palermo R, Grazioli P, Campese AF, Talora C, Bellavia D, D'Amati G, Besharat ZM, Nicoletti C, Siebel CW, Choy L, Rustighi A, Sal GD, Screpanti I, Checquolo S. Franciosa G, et al. Among authors: siebel cw. Oncogene. 2016 Sep 8;35(36):4741-51. doi: 10.1038/onc.2016.5. Epub 2016 Feb 15. Oncogene. 2016. PMID: 26876201 Free PMC article.
Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression.
Brandt S, Ballhause TM, Bernhardt A, Becker A, Salaru D, Le-Deffge HM, Fehr A, Fu Y, Philipsen L, Djudjaj S, Müller AJ, Kramann R, Ibrahim M, Geffers R, Siebel C, Isermann B, Heidel FH, Lindquist JA, Mertens PR. Brandt S, et al. J Am Soc Nephrol. 2020 Nov;31(11):2589-2608. doi: 10.1681/ASN.2019121289. Epub 2020 Aug 28. J Am Soc Nephrol. 2020. PMID: 32859670 Free PMC article.
70 results