Lang J - Search Results

1

The development of human immune system mice and their use to study tolerance and autoimmunity.

Alves da Costa T, Lang J, Torres RM, Pelanda R. Alves da Costa T, et al. Among authors: lang j. J Transl Autoimmun. 2019 Nov 11;2:100021. doi: 10.1016/j.jtauto.2019.100021. eCollection 2019 Dec. J Transl Autoimmun. 2019. PMID: 32743507 Free PMC article. Review.

2

Generation of hematopoietic humanized mice in the newborn BALB/c-Rag2null Il2rγnull mouse model: a multivariable optimization approach.

Lang J, Weiss N, Freed BM, Torres RM, Pelanda R. Lang J, et al. Clin Immunol. 2011 Jul;140(1):102-16. doi: 10.1016/j.clim.2011.04.002. Epub 2011 Apr 14. Clin Immunol. 2011. PMID: 21536497 Free PMC article.

3

Studies of lymphocyte reconstitution in a humanized mouse model reveal a requirement of T cells for human B cell maturation.

Lang J, Kelly M, Freed BM, McCarter MD, Kedl RM, Torres RM, Pelanda R. Lang J, et al. J Immunol. 2013 Mar 1;190(5):2090-101. doi: 10.4049/jimmunol.1202810. Epub 2013 Jan 18. J Immunol. 2013. PMID: 23335750 Free PMC article.

4

Receptor editing and genetic variability in human autoreactive B cells.

Lang J, Ota T, Kelly M, Strauch P, Freed BM, Torres RM, Nemazee D, Pelanda R. Lang J, et al. J Exp Med. 2016 Jan 11;213(1):93-108. doi: 10.1084/jem.20151039. Epub 2015 Dec 22. J Exp Med. 2016. PMID: 26694971 Free PMC article.

5

Replacing mouse BAFF with human BAFF does not improve B-cell maturation in hematopoietic humanized mice.

Lang J, Zhang B, Kelly M, Peterson JN, Barbee J, Freed BM, Di Santo JP, Matsuda JL, Torres RM, Pelanda R. Lang J, et al. Blood Adv. 2017 Dec 19;1(27):2729-2741. doi: 10.1182/bloodadvances.2017010090. eCollection 2017 Dec 26. Blood Adv. 2017. PMID: 29296925 Free PMC article.

6

Epstein-Barr Virus Type 2 Infects T Cells and Induces B Cell Lymphomagenesis in Humanized Mice.

Coleman CB, Lang J, Sweet LA, Smith NA, Freed BM, Pan Z, Haverkos B, Pelanda R, Rochford R. Coleman CB, et al. Among authors: lang j. J Virol. 2018 Oct 12;92(21):e00813-18. doi: 10.1128/JVI.00813-18. Print 2018 Nov 1. J Virol. 2018. PMID: 30089703 Free PMC article.

7

Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts.

Capasso A, Lang J, Pitts TM, Jordan KR, Lieu CH, Davis SL, Diamond JR, Kopetz S, Barbee J, Peterson J, Freed BM, Yacob BW, Bagby SM, Messersmith WA, Slansky JE, Pelanda R, Eckhardt SG. Capasso A, et al. Among authors: lang j. J Immunother Cancer. 2019 Feb 8;7(1):37. doi: 10.1186/s40425-019-0518-z. J Immunother Cancer. 2019. PMID: 30736857 Free PMC article.

8

RX-5902, a novel β-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer.

Tentler JJ, Lang J, Capasso A, Kim DJ, Benaim E, Lee YB, Eisen A, Bagby SM, Hartman SJ, Yacob BW, Gittleman B, Pitts TM, Pelanda R, Eckhardt SG, Diamond JR. Tentler JJ, et al. Among authors: lang j. BMC Cancer. 2020 Nov 4;20(1):1063. doi: 10.1186/s12885-020-07500-1. BMC Cancer. 2020. PMID: 33148223 Free PMC article.

9

Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice.

Alves da Costa T, Peterson JN, Lang J, Shulman J, Liang X, Freed BM, Boackle SA, Lauzurica P, Torres RM, Pelanda R. Alves da Costa T, et al. Among authors: lang j. Proc Natl Acad Sci U S A. 2021 Apr 20;118(16):e2021570118. doi: 10.1073/pnas.2021570118. Proc Natl Acad Sci U S A. 2021. PMID: 33850015 Free PMC article.

10

Testing Cancer Immunotherapy in a Human Immune System Mouse Model: Correlating Treatment Responses to Human Chimerism, Therapeutic Variables and Immune Cell Phenotypes.

Marín-Jiménez JA, Capasso A, Lewis MS, Bagby SM, Hartman SJ, Shulman J, Navarro NM, Yu H, Rivard CJ, Wang X, Barkow JC, Geng D, Kar A, Yingst A, Tufa DM, Dolan JT, Blatchford PJ, Freed BM, Torres RM, Davila E, Slansky JE, Pelanda R, Eckhardt SG, Messersmith WA, Diamond JR, Lieu CH, Verneris MR, Wang JH, Kiseljak-Vassiliades K, Pitts TM, Lang J. Marín-Jiménez JA, et al. Among authors: lang j. Front Immunol. 2021 Mar 29;12:607282. doi: 10.3389/fimmu.2021.607282. eCollection 2021. Front Immunol. 2021. PMID: 33854497 Free PMC article.

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