Sindelar DK - Search Results

1

The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling.

Worth AA, Shoop R, Tye K, Feetham CH, D'Agostino G, Dodd GT, Reimann F, Gribble FM, Beebe EC, Dunbar JD, Alexander-Chacko JT, Sindelar DK, Coskun T, Emmerson PJ, Luckman SM. Worth AA, et al. Among authors: sindelar dk. Elife. 2020 Jul 29;9:e55164. doi: 10.7554/eLife.55164. Elife. 2020. PMID: 32723474 Free PMC article.

2

The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL.

Emmerson PJ, Wang F, Du Y, Liu Q, Pickard RT, Gonciarz MD, Coskun T, Hamang MJ, Sindelar DK, Ballman KK, Foltz LA, Muppidi A, Alsina-Fernandez J, Barnard GC, Tang JX, Liu X, Mao X, Siegel R, Sloan JH, Mitchell PJ, Zhang BB, Gimeno RE, Shan B, Wu X. Emmerson PJ, et al. Among authors: sindelar dk. Nat Med. 2017 Oct;23(10):1215-1219. doi: 10.1038/nm.4393. Epub 2017 Aug 28. Nat Med. 2017. PMID: 28846098

3

Activation of mesolimbic dopamine neurons during novel and daily limited access to palatable food is blocked by the opioid antagonist LY255582.

Sahr AE, Sindelar DK, Alexander-Chacko JT, Eastwood BJ, Mitch CH, Statnick MA. Sahr AE, et al. Among authors: sindelar dk. Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R463-71. doi: 10.1152/ajpregu.00390.2007. Epub 2008 Jun 4. Am J Physiol Regul Integr Comp Physiol. 2008. PMID: 18525013 Free article.

4

LLY-2707, a novel nonsteroidal glucocorticoid antagonist that reduces atypical antipsychotic-associated weight gain in rats.

Sindelar DK, Carson MW, Morin M, Shaw J, Barr RJ, Need A, Alexander-Chacko J, Coghlan M, Gehlert DR. Sindelar DK, et al. J Pharmacol Exp Ther. 2014 Jan;348(1):192-201. doi: 10.1124/jpet.113.205864. Epub 2013 Oct 25. J Pharmacol Exp Ther. 2014. PMID: 24163440

5

The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats.

Need AB, Davis RJ, Alexander-Chacko JT, Eastwood B, Chernet E, Phebus LA, Sindelar DK, Nomikos GG. Need AB, et al. Among authors: sindelar dk. Psychopharmacology (Berl). 2006 Jan;184(1):26-35. doi: 10.1007/s00213-005-0234-x. Epub 2005 Nov 18. Psychopharmacology (Berl). 2006. PMID: 16328376

6

Central H3R activation by thioperamide does not affect energy balance.

Sindelar DK, Shepperd ML, Pickard RT, Alexander-Chacko J, Dill MJ, Cramer JW, Smith DP, Gadski R. Sindelar DK, et al. Pharmacol Biochem Behav. 2004 Jun;78(2):275-83. doi: 10.1016/j.pbb.2004.03.019. Pharmacol Biochem Behav. 2004. PMID: 15219768

7

Dual Exosite-binding Inhibitors of Insulin-degrading Enzyme Challenge Its Role as the Primary Mediator of Insulin Clearance in Vivo.

Durham TB, Toth JL, Klimkowski VJ, Cao JX, Siesky AM, Alexander-Chacko J, Wu GY, Dixon JT, McGee JE, Wang Y, Guo SY, Cavitt RN, Schindler J, Thibodeaux SJ, Calvert NA, Coghlan MJ, Sindelar DK, Christe M, Kiselyov VV, Michael MD, Sloop KW. Durham TB, et al. Among authors: sindelar dk. J Biol Chem. 2015 Aug 14;290(33):20044-59. doi: 10.1074/jbc.M115.638205. Epub 2015 Jun 17. J Biol Chem. 2015. PMID: 26085101 Free PMC article.

8

5-HT1A receptor antagonists reduce food intake and body weight by reducing total meals with no conditioned taste aversion.

Dill MJ, Shaw J, Cramer J, Sindelar DK. Dill MJ, et al. Among authors: sindelar dk. Pharmacol Biochem Behav. 2013 Nov;112:1-8. doi: 10.1016/j.pbb.2013.09.003. Epub 2013 Sep 21. Pharmacol Biochem Behav. 2013. PMID: 24064183

9

Synthesis and SAR of novel histamine H3 receptor antagonists.

Jesudason CD, Beavers LS, Cramer JW, Dill J, Finley DR, Lindsley CW, Stevens FC, Gadski RA, Oldham SW, Pickard RT, Siedem CS, Sindelar DK, Singh A, Watson BM, Hipskind PA. Jesudason CD, et al. Among authors: sindelar dk. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3415-8. doi: 10.1016/j.bmcl.2006.04.004. Epub 2006 May 3. Bioorg Med Chem Lett. 2006. PMID: 16677814

10

Indole Glucocorticoid Receptor Antagonists Active in a Model of Dyslipidemia Act via a Unique Association with an Agonist Binding Site.

Luz JG, Carson MW, Condon B, Clawson D, Pustilnik A, Kohlman DT, Barr RJ, Bean JS, Dill MJ, Sindelar DK, Maletic M, Coghlan MJ. Luz JG, et al. Among authors: sindelar dk. J Med Chem. 2015 Aug 27;58(16):6607-18. doi: 10.1021/acs.jmedchem.5b00736. Epub 2015 Aug 7. J Med Chem. 2015. PMID: 26218343

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