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Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration.
Ott M, Tomaszowski KH, Marisetty A, Kong LY, Wei J, Duna M, Blumberg K, Ji X, Jacobs C, Fuller GN, Langford LA, Huse JT, Long JP, Hu J, Li S, Weinberg JS, Prabhu SS, Sawaya R, Ferguson S, Rao G, Lang FF, Curran MA, Heimberger AB. Ott M, et al. Among authors: wei j. JCI Insight. 2020 Sep 3;5(17):e134386. doi: 10.1172/jci.insight.134386. JCI Insight. 2020. PMID: 32721947 Free PMC article.
Topotecan enhances immune clearance of gliomas.
Wei J, DeAngulo G, Sun W, Hussain SF, Vasquez H, Jordan J, Weinberg J, Wolff J, Koshkina N, Heimberger AB. Wei J, et al. Cancer Immunol Immunother. 2009 Feb;58(2):259-70. doi: 10.1007/s00262-008-0550-1. Epub 2008 Jul 2. Cancer Immunol Immunother. 2009. PMID: 18594817 Free PMC article.
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells.
Kong LY, Abou-Ghazal MK, Wei J, Chakraborty A, Sun W, Qiao W, Fuller GN, Fokt I, Grimm EA, Schmittling RJ, Archer GE Jr, Sampson JH, Priebe W, Heimberger AB. Kong LY, et al. Among authors: wei j. Clin Cancer Res. 2008 Sep 15;14(18):5759-68. doi: 10.1158/1078-0432.CCR-08-0377. Clin Cancer Res. 2008. PMID: 18794085 Free PMC article.
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