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Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
Rathert P, Roth M, Neumann T, Muerdter F, Roe JS, Muhar M, Deswal S, Cerny-Reiterer S, Peter B, Jude J, Hoffmann T, Boryń ŁM, Axelsson E, Schweifer N, Tontsch-Grunt U, Dow LE, Gianni D, Pearson M, Valent P, Stark A, Kraut N, Vakoc CR, Zuber J. Rathert P, et al. Among authors: neumann t. Nature. 2015 Sep 24;525(7570):543-547. doi: 10.1038/nature14898. Epub 2015 Sep 14. Nature. 2015. PMID: 26367798 Free PMC article.
Thiol-linked alkylation of RNA to assess expression dynamics.
Herzog VA, Reichholf B, Neumann T, Rescheneder P, Bhat P, Burkard TR, Wlotzka W, von Haeseler A, Zuber J, Ameres SL. Herzog VA, et al. Among authors: neumann t. Nat Methods. 2017 Dec;14(12):1198-1204. doi: 10.1038/nmeth.4435. Epub 2017 Sep 25. Nat Methods. 2017. PMID: 28945705 Free PMC article.
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis.
Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, Rescheneder P, Lipp JJ, Herzog VA, Reichholf B, Cisneros DA, Hoffmann T, Schlapansky MF, Bhat P, von Haeseler A, Köcher T, Obenauf AC, Popow J, Ameres SL, Zuber J. Muhar M, et al. Among authors: neumann t. Science. 2018 May 18;360(6390):800-805. doi: 10.1126/science.aao2793. Epub 2018 Apr 5. Science. 2018. PMID: 29622725 Free PMC article.
Sequencing cell-type-specific transcriptomes with SLAM-ITseq.
Matsushima W, Herzog VA, Neumann T, Gapp K, Zuber J, Ameres SL, Miska EA. Matsushima W, et al. Among authors: neumann t. Nat Protoc. 2019 Aug;14(8):2261-2278. doi: 10.1038/s41596-019-0179-x. Epub 2019 Jun 26. Nat Protoc. 2019. PMID: 31243395 Free PMC article.
Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters.
Umkehrer C, Holstein F, Formenti L, Jude J, Froussios K, Neumann T, Cronin SM, Haas L, Lipp JJ, Burkard TR, Fellner M, Wiesner T, Zuber J, Obenauf AC. Umkehrer C, et al. Among authors: neumann t. Nat Biotechnol. 2021 Feb;39(2):174-178. doi: 10.1038/s41587-020-0614-0. Epub 2020 Jul 27. Nat Biotechnol. 2021. PMID: 32719478
738 results