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Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes.
Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, Wahlquist C, Kreymerman A, Vu M, Amatya PL, Behrens CS, Ranjbarvaziri S, Maas RGC, Greenhaw M, Bernstein D, Wu JC, Bers DM, Eschenhagen T, Metallo CM, Mercola M. Feyen DAM, et al. Among authors: mercola m. Cell Rep. 2020 Jul 21;32(3):107925. doi: 10.1016/j.celrep.2020.107925. Cell Rep. 2020. PMID: 32697997 Free PMC article.
Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity.
McKeithan WL, Feyen DAM, Bruyneel AAN, Okolotowicz KJ, Ryan DA, Sampson KJ, Potet F, Savchenko A, Gómez-Galeno J, Vu M, Serrano R, George AL Jr, Kass RS, Cashman JR, Mercola M. McKeithan WL, et al. Among authors: mercola m. Cell Stem Cell. 2020 Nov 5;27(5):813-821.e6. doi: 10.1016/j.stem.2020.08.003. Epub 2020 Sep 14. Cell Stem Cell. 2020. PMID: 32931730 Free PMC article.
Human iPSC modeling of heart disease for drug development.
Hnatiuk AP, Briganti F, Staudt DW, Mercola M. Hnatiuk AP, et al. Among authors: mercola m. Cell Chem Biol. 2021 Mar 18;28(3):271-282. doi: 10.1016/j.chembiol.2021.02.016. Cell Chem Biol. 2021. PMID: 33740432 Free PMC article. Review.
High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells.
Sharma A, Burridge PW, McKeithan WL, Serrano R, Shukla P, Sayed N, Churko JM, Kitani T, Wu H, Holmström A, Matsa E, Zhang Y, Kumar A, Fan AC, Del Álamo JC, Wu SM, Moslehi JJ, Mercola M, Wu JC. Sharma A, et al. Among authors: mercola m. Sci Transl Med. 2017 Feb 15;9(377):eaaf2584. doi: 10.1126/scitranslmed.aaf2584. Sci Transl Med. 2017. PMID: 28202772 Free PMC article.
CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes.
Chirikian O, Goodyer WR, Dzilic E, Serpooshan V, Buikema JW, McKeithan W, Wu H, Li G, Lee S, Merk M, Galdos F, Beck A, Ribeiro AJS, Paige S, Mercola M, Wu JC, Pruitt BL, Wu SM. Chirikian O, et al. Among authors: mercola m. Sci Rep. 2021 Feb 4;11(1):3026. doi: 10.1038/s41598-021-81860-x. Sci Rep. 2021. PMID: 33542270 Free PMC article.
175 results