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Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes.
Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, Wahlquist C, Kreymerman A, Vu M, Amatya PL, Behrens CS, Ranjbarvaziri S, Maas RGC, Greenhaw M, Bernstein D, Wu JC, Bers DM, Eschenhagen T, Metallo CM, Mercola M. Feyen DAM, et al. Among authors: mckeithan wl. Cell Rep. 2020 Jul 21;32(3):107925. doi: 10.1016/j.celrep.2020.107925. Cell Rep. 2020. PMID: 32697997 Free PMC article.
Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity.
McKeithan WL, Feyen DAM, Bruyneel AAN, Okolotowicz KJ, Ryan DA, Sampson KJ, Potet F, Savchenko A, Gómez-Galeno J, Vu M, Serrano R, George AL Jr, Kass RS, Cashman JR, Mercola M. McKeithan WL, et al. Cell Stem Cell. 2020 Nov 5;27(5):813-821.e6. doi: 10.1016/j.stem.2020.08.003. Epub 2020 Sep 14. Cell Stem Cell. 2020. PMID: 32931730 Free PMC article.
A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay.
Seeger T, Shrestha R, Lam CK, Chen C, McKeithan WL, Lau E, Wnorowski A, McMullen G, Greenhaw M, Lee J, Oikonomopoulos A, Lee S, Yang H, Mercola M, Wheeler M, Ashley EA, Yang F, Karakikes I, Wu JC. Seeger T, et al. Among authors: mckeithan wl. Circulation. 2019 Feb 5;139(6):799-811. doi: 10.1161/CIRCULATIONAHA.118.034624. Circulation. 2019. PMID: 30586709 Free PMC article.
Human iPSC-derived cardiomyocytes and pyridyl-phenyl mexiletine analogs.
Johnson M, Gomez-Galeno J, Ryan D, Okolotowicz K, McKeithan WL, Sampson KJ, Kass RS, Mercola M, Cashman JR. Johnson M, et al. Among authors: mckeithan wl. Bioorg Med Chem Lett. 2021 Aug 15;46:128162. doi: 10.1016/j.bmcl.2021.128162. Epub 2021 May 29. Bioorg Med Chem Lett. 2021. PMID: 34062251
18 results