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The regulation of glucose and lipid homeostasis via PLTP as a mediator of BAT-liver communication.
Sponton CH, Hosono T, Taura J, Jedrychowski MP, Yoneshiro T, Wang Q, Takahashi M, Matsui Y, Ikeda K, Oguri Y, Tajima K, Shinoda K, Pradhan RN, Chen Y, Brown Z, Roberts LS, Ward CC, Taoka H, Yokoyama Y, Watanabe M, Karasawa H, Nomura DK, Kajimura S. Sponton CH, et al. Among authors: matsui y. EMBO Rep. 2020 Sep 3;21(9):e49828. doi: 10.15252/embr.201949828. Epub 2020 Jul 16. EMBO Rep. 2020. PMID: 32672883 Free PMC article.
Novel Antibody Exerts Antitumor Effect through Downregulation of CD147 and Activation of Multiple Stress Signals.
Fukuchi K, Nanai K, Yuita H, Maru C, Tsukada J, Ishigami M, Nagai Y, Nakano Y, Yoshimura C, Yoneda K, Amano M, Nakamura K, Oda Y, Nishigohri H, Yamamoto S, Ohnishi-Totoki Y, Inaki K, Komori H, Nakano R, Kanari Y, Nishida A, Matsui Y, Funo S, Takahashi S, Ohtsuka T, Agatsuma T. Fukuchi K, et al. Among authors: matsui y. J Oncol. 2022 Nov 4;2022:3552793. doi: 10.1155/2022/3552793. eCollection 2022. J Oncol. 2022. PMID: 36385956 Free PMC article.
Indoline derivatives I: synthesis and factor Xa (FXa) inhibitory activities.
Noguchi T, Tanaka N, Nishimata T, Goto R, Hayakawa M, Sugidachi A, Ogawa T, Asai F, Matsui Y, Fujimoto K. Noguchi T, et al. Among authors: matsui y. Chem Pharm Bull (Tokyo). 2006 Feb;54(2):163-74. doi: 10.1248/cpb.54.163. Chem Pharm Bull (Tokyo). 2006. PMID: 16462058 Free article.
Structure-Activity Relationship Studies of 3- or 4-Pyridine Derivatives of DS-6930.
Shinozuka T, Tsukada T, Fujii K, Tokumaru E, Matsui Y, Wakimoto S, Ogata T, Araki K, Sawamura R, Watanabe N, Mori M, Tanaka J. Shinozuka T, et al. Among authors: matsui y. ACS Med Chem Lett. 2019 Feb 26;10(3):358-362. doi: 10.1021/acsmedchemlett.8b00645. eCollection 2019 Mar 14. ACS Med Chem Lett. 2019. PMID: 30891140 Free PMC article.
Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold.
Kawai J, Ota M, Ohki H, Toki T, Suzuki M, Shimada T, Matsui S, Inoue H, Sugihara C, Matsuhashi N, Matsui Y, Takaishi S, Nakayama K. Kawai J, et al. Among authors: matsui s, matsui y. ACS Med Chem Lett. 2019 May 24;10(6):893-898. doi: 10.1021/acsmedchemlett.9b00069. eCollection 2019 Jun 13. ACS Med Chem Lett. 2019. PMID: 31223444 Free PMC article.
Discovery of a Novel ATP-Competitive MEK Inhibitor DS03090629 that Overcomes Resistance Conferred by BRAF Overexpression in BRAF-Mutated Melanoma.
Takano K, Munehira Y, Hatanaka M, Murakami R, Shibata Y, Shida T, Takeuchi K, Takechi S, Tabata T, Shimada T, Kishikawa S, Matsui Y, Ubukata O, Seki T, Kaneta Y. Takano K, et al. Among authors: matsui y. Mol Cancer Ther. 2023 Mar 2;22(3):317-332. doi: 10.1158/1535-7163.MCT-22-0306. Mol Cancer Ther. 2023. PMID: 36622773
A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1.
Matsui Y, Yasumatsu I, Yoshida KI, Iimura S, Ikeno Y, Nawano T, Fukano H, Ubukata O, Hanzawa H, Tanzawa F, Isoyama T. Matsui Y, et al. Acta Crystallogr F Struct Biol Commun. 2018 Mar 1;74(Pt 3):156-160. doi: 10.1107/S2053230X18002108. Epub 2018 Feb 26. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29497019 Free PMC article.
Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor.
Nakamura Y, Fujimoto T, Ogawa Y, Sugita C, Miyazaki S, Tamaki K, Takahashi M, Matsui Y, Nagayama T, Manabe K, Mizuno M, Masubuchi N, Chiba K, Nishi T. Nakamura Y, et al. Among authors: matsui y. ACS Med Chem Lett. 2012 Aug 18;3(9):754-8. doi: 10.1021/ml300168e. eCollection 2012 Sep 13. ACS Med Chem Lett. 2012. PMID: 24900544 Free PMC article.
2,628 results