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PPARβ/δ-dependent MSC metabolism determines their immunoregulatory properties.
Contreras-Lopez RA, Elizondo-Vega R, Torres MJ, Vega-Letter AM, Luque-Campos N, Paredes-Martinez MJ, Pradenas C, Tejedor G, Oyarce K, Salgado M, Jorgensen C, Khoury M, Kronke G, Garcia-Robles MA, Altamirano C, Luz-Crawford P, Djouad F. Contreras-Lopez RA, et al. Among authors: torres mj. Sci Rep. 2020 Jul 10;10(1):11423. doi: 10.1038/s41598-020-68347-x. Sci Rep. 2020. PMID: 32651456 Free PMC article.
HIF1α-dependent metabolic reprogramming governs mesenchymal stem/stromal cell immunoregulatory functions.
Contreras-Lopez R, Elizondo-Vega R, Paredes MJ, Luque-Campos N, Torres MJ, Tejedor G, Vega-Letter AM, Figueroa-Valdés A, Pradenas C, Oyarce K, Jorgensen C, Khoury M, Garcia-Robles MLA, Altamirano C, Djouad F, Luz-Crawford P. Contreras-Lopez R, et al. Among authors: torres mj. FASEB J. 2020 Jun;34(6):8250-8264. doi: 10.1096/fj.201902232R. Epub 2020 Apr 25. FASEB J. 2020. PMID: 32333618
The ATP synthase inhibition induces an AMPK-dependent glycolytic switch of mesenchymal stem cells that enhances their immunotherapeutic potential.
Contreras-Lopez R, Elizondo-Vega R, Luque-Campos N, Torres MJ, Pradenas C, Tejedor G, Paredes-Martínez MJ, Vega-Letter AM, Campos-Mora M, Rigual-Gonzalez Y, Oyarce K, Salgado M, Jorgensen C, Khoury M, Garcia-Robles MLÁ, Altamirano C, Djouad F, Luz-Crawford P. Contreras-Lopez R, et al. Among authors: torres mj. Theranostics. 2021 Jan 1;11(1):445-460. doi: 10.7150/thno.51631. eCollection 2021. Theranostics. 2021. PMID: 33391485 Free PMC article.
The immunosuppressive signature of menstrual blood mesenchymal stem cells entails opposite effects on experimental arthritis and graft versus host diseases.
Luz-Crawford P, Torres MJ, Noël D, Fernandez A, Toupet K, Alcayaga-Miranda F, Tejedor G, Jorgensen C, Illanes SE, Figueroa FE, Djouad F, Khoury M. Luz-Crawford P, et al. Among authors: torres mj. Stem Cells. 2016 Feb;34(2):456-69. doi: 10.1002/stem.2244. Epub 2015 Dec 3. Stem Cells. 2016. PMID: 26528946
Innate immune system and preeclampsia.
Perez-Sepulveda A, Torres MJ, Khoury M, Illanes SE. Perez-Sepulveda A, et al. Among authors: torres mj. Front Immunol. 2014 May 26;5:244. doi: 10.3389/fimmu.2014.00244. eCollection 2014. Front Immunol. 2014. PMID: 24904591 Free PMC article. Review.
609 results