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MKK6 controls T3-mediated browning of white adipose tissue.
Matesanz N, Bernardo E, Acín-Pérez R, Manieri E, Pérez-Sieira S, Hernández-Cosido L, Montalvo-Romeral V, Mora A, Rodríguez E, Leiva-Vega L, Lechuga-Vieco AV, Ruiz-Cabello J, Torres JL, Crespo-Ruiz M, Centeno F, Álvarez CV, Marcos M, Enríquez JA, Nogueiras R, Sabio G. Matesanz N, et al. Nat Commun. 2017 Oct 11;8(1):856. doi: 10.1038/s41467-017-00948-z. Nat Commun. 2017. PMID: 29021624 Free PMC article.
Mitochondria Bound to Lipid Droplets Have Unique Bioenergetics, Composition, and Dynamics that Support Lipid Droplet Expansion.
Benador IY, Veliova M, Mahdaviani K, Petcherski A, Wikstrom JD, Assali EA, Acín-Pérez R, Shum M, Oliveira MF, Cinti S, Sztalryd C, Barshop WD, Wohlschlegel JA, Corkey BE, Liesa M, Shirihai OS. Benador IY, et al. Cell Metab. 2018 Apr 3;27(4):869-885.e6. doi: 10.1016/j.cmet.2018.03.003. Cell Metab. 2018. PMID: 29617645 Free PMC article.
Sex-specific metabolic functions of adipose Lipocalin-2.
Chella Krishnan K, Sabir S, Shum M, Meng Y, Acín-Pérez R, Lang JM, Floyd RR, Vergnes L, Seldin MM, Fuqua BK, Jayasekera DW, Nand SK, Anum DC, Pan C, Stiles L, Péterfy M, Reue K, Liesa M, Lusis AJ. Chella Krishnan K, et al. Mol Metab. 2019 Dec;30:30-47. doi: 10.1016/j.molmet.2019.09.009. Epub 2019 Sep 27. Mol Metab. 2019. PMID: 31767179 Free PMC article.
A novel approach to measure mitochondrial respiration in frozen biological samples.
Acin-Perez R, Benador IY, Petcherski A, Veliova M, Benavides GA, Lagarrigue S, Caudal A, Vergnes L, Murphy AN, Karamanlidis G, Tian R, Reue K, Wanagat J, Sacks H, Amati F, Darley-Usmar VM, Liesa M, Divakaruni AS, Stiles L, Shirihai OS. Acin-Perez R, et al. EMBO J. 2020 Jul 1;39(13):e104073. doi: 10.15252/embj.2019104073. Epub 2020 May 20. EMBO J. 2020. PMID: 32432379 Free PMC article.
Na+ controls hypoxic signalling by the mitochondrial respiratory chain.
Hernansanz-Agustín P, Choya-Foces C, Carregal-Romero S, Ramos E, Oliva T, Villa-Piña T, Moreno L, Izquierdo-Álvarez A, Cabrera-García JD, Cortés A, Lechuga-Vieco AV, Jadiya P, Navarro E, Parada E, Palomino-Antolín A, Tello D, Acín-Pérez R, Rodríguez-Aguilera JC, Navas P, Cogolludo Á, López-Montero I, Martínez-Del-Pozo Á, Egea J, López MG, Elrod JW, Ruíz-Cabello J, Bogdanova A, Enríquez JA, Martínez-Ruiz A. Hernansanz-Agustín P, et al. Nature. 2020 Oct;586(7828):287-291. doi: 10.1038/s41586-020-2551-y. Epub 2020 Jul 29. Nature. 2020. PMID: 32728214 Free PMC article.
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity.
Acín-Pérez R, Iborra S, Martí-Mateos Y, Cook ECL, Conde-Garrosa R, Petcherski A, Muñoz MDM, Martínez de Mena R, Krishnan KC, Jiménez C, Bolaños JP, Laakso M, Lusis AJ, Shirihai OS, Sancho D, Enríquez JA. Acín-Pérez R, et al. Nat Metab. 2020 Sep;2(9):974-988. doi: 10.1038/s42255-020-00273-8. Epub 2020 Sep 17. Nat Metab. 2020. PMID: 32943786 Free PMC article.
Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling.
Veliova M, Ferreira CM, Benador IY, Jones AE, Mahdaviani K, Brownstein AJ, Desousa BR, Acín-Pérez R, Petcherski A, Assali EA, Stiles L, Divakaruni AS, Prentki M, Corkey BE, Liesa M, Oliveira MF, Shirihai OS. Veliova M, et al. EMBO Rep. 2020 Dec 3;21(12):e49634. doi: 10.15252/embr.201949634. Epub 2020 Dec 4. EMBO Rep. 2020. PMID: 33275313 Free PMC article.
84 results