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Hydroxychloroquine Proves Ineffective in Hamsters and Macaques Infected with SARS-CoV-2.
Rosenke K, Jarvis MA, Feldmann F, Schwarz B, Okumura A, Lovaglio J, Saturday G, Hanley PW, Meade-White K, Williamson BN, Hansen F, Perez-Perez L, Leventhal S, Tang-Huau TL, Nason M, Callison J, Haddock E, Scott D, Sewell G, Bosio CM, Hawman D, de Wit E, Feldmann H. Rosenke K, et al. Among authors: bosio cm. bioRxiv [Preprint]. 2020 Jun 11:2020.06.10.145144. doi: 10.1101/2020.06.10.145144. bioRxiv. 2020. PMID: 32577633 Free PMC article. Preprint.
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2.
Williamson BN, Feldmann F, Schwarz B, Meade-White K, Porter DP, Schulz J, van Doremalen N, Leighton I, Kwe Yinda C, Pérez-Pérez L, Okumura A, Lovaglio J, Hanley PW, Saturday G, Bosio CM, Anzick S, Barbian K, Cihlar T, Martens C, Scott DP, Munster VJ, de Wit E. Williamson BN, et al. Among authors: bosio cm. bioRxiv [Preprint]. 2020 Apr 22:2020.04.15.043166. doi: 10.1101/2020.04.15.043166. bioRxiv. 2020. Update in: Nature. 2020 Sep;585(7824):273-276. doi: 10.1038/s41586-020-2423-5. PMID: 32511319 Free PMC article. Updated. Preprint.
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2.
Williamson BN, Feldmann F, Schwarz B, Meade-White K, Porter DP, Schulz J, van Doremalen N, Leighton I, Yinda CK, Pérez-Pérez L, Okumura A, Lovaglio J, Hanley PW, Saturday G, Bosio CM, Anzick S, Barbian K, Cihlar T, Martens C, Scott DP, Munster VJ, de Wit E. Williamson BN, et al. Among authors: bosio cm. Nature. 2020 Sep;585(7824):273-276. doi: 10.1038/s41586-020-2423-5. Epub 2020 Jun 9. Nature. 2020. PMID: 32516797 Free PMC article.
Hydroxychloroquine prophylaxis and treatment is ineffective in macaque and hamster SARS-CoV-2 disease models.
Rosenke K, Jarvis MA, Feldmann F, Schwarz B, Okumura A, Lovaglio J, Saturday G, Hanley PW, Meade-White K, Williamson BN, Hansen F, Perez-Perez L, Leventhal S, Tang-Huau TL, Callison J, Haddock E, Stromberg KA, Scott D, Sewell G, Bosio CM, Hawman D, de Wit E, Feldmann H. Rosenke K, et al. Among authors: bosio cm. JCI Insight. 2020 Dec 3;5(23):e143174. doi: 10.1172/jci.insight.143174. JCI Insight. 2020. PMID: 33090972 Free PMC article.
Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model.
Rosenke K, Hansen F, Schwarz B, Feldmann F, Haddock E, Rosenke R, Barbian K, Meade-White K, Okumura A, Leventhal S, Hawman DW, Ricotta E, Bosio CM, Martens C, Saturday G, Feldmann H, Jarvis MA. Rosenke K, et al. Among authors: bosio cm. Nat Commun. 2021 Apr 16;12(1):2295. doi: 10.1038/s41467-021-22580-8. Nat Commun. 2021. PMID: 33863887 Free PMC article.
Subcutaneous remdesivir administration prevents interstitial pneumonia in rhesus macaques inoculated with SARS-CoV-2.
Williamson BN, Pérez-Pérez L, Schwarz B, Feldmann F, Holbrook MG, Singh M, Lye DS, Babusis D, Subramanian R, Haddock E, Okumura A, Hanley PW, Lovaglio J, Bosio CM, Porter DP, Cihlar T, Mackman RL, Saturday G, de Wit E. Williamson BN, et al. Among authors: bosio cm. Antiviral Res. 2022 Feb;198:105246. doi: 10.1016/j.antiviral.2022.105246. Epub 2022 Jan 13. Antiviral Res. 2022. PMID: 35032523 Free PMC article.
Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques.
Speranza E, Purushotham JN, Port JR, Schwarz B, Flagg M, Williamson BN, Feldmann F, Singh M, Pérez-Pérez L, Sturdevant GL, Roberts LM, Carmody A, Schulz JE, van Doremalen N, Okumura A, Lovaglio J, Hanley PW, Shaia C, Germain RN, Best SM, Munster VJ, Bosio CM, de Wit E. Speranza E, et al. Among authors: bosio cm. Life Sci Alliance. 2022 Jan 17;5(4):e202101314. doi: 10.26508/lsa.202101314. Print 2022 Apr. Life Sci Alliance. 2022. PMID: 35039442 Free PMC article.
Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model.
Rosenke K, Hansen F, Schwarz B, Feldmann F, Haddock E, Rosenke R, Meade-White K, Okumura A, Leventhal S, Hawman DW, Ricotta E, Bosio CM, Saturday G, Feldmann H, Jarvis MA. Rosenke K, et al. Among authors: bosio cm. Res Sq [Preprint]. 2020 Oct 8:rs.3.rs-86289. doi: 10.21203/rs.3.rs-86289/v1. Res Sq. 2020. Update in: Nat Commun. 2021 Apr 16;12(1):2295. doi: 10.1038/s41467-021-22580-8. PMID: 33052329 Free PMC article. Updated. Preprint.
112 results