Qian M - Search Results

1

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.

Wong MY, Lewis M, Doherty JJ, Shi Y, Cashikar AG, Amelianchik A, Tymchuk S, Sullivan PM, Qian M, Covey DF, Petsko GA, Holtzman DM, Paul SM, Luo W. Wong MY, et al. Among authors: qian m. J Neuroinflammation. 2020 Jun 17;17(1):192. doi: 10.1186/s12974-020-01869-3. J Neuroinflammation. 2020. PMID: 32552741 Free PMC article.

2

The Efficient and Enantiospecific Total Synthesis of Cyclopenta[b]phenanthrenes Structurally-related to Neurosteroids.

Qian M, Covey DF. Qian M, et al. Adv Synth Catal. 2010 Oct 9;352(11-12):2057-2061. doi: 10.1002/adsc.201000370. Adv Synth Catal. 2010. PMID: 22022301 Free PMC article.

3

Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone.

Qian M, Krishnan K, Kudova E, Li P, Manion BD, Taylor A, Elias G, Akk G, Evers AS, Zorumski CF, Mennerick S, Covey DF. Qian M, et al. J Med Chem. 2014 Jan 9;57(1):171-90. doi: 10.1021/jm401577c. Epub 2013 Dec 24. J Med Chem. 2014. PMID: 24328079 Free PMC article.

4

Comparison of Steroid Modulation of Spontaneous Inhibitory Postsynaptic Currents in Cultured Hippocampal Neurons and Steady-State Single-Channel Currents from Heterologously Expressed α1β2γ2L GABA(A) Receptors.

Chakrabarti S, Qian M, Krishnan K, Covey DF, Mennerick S, Akk G. Chakrabarti S, et al. Among authors: qian m. Mol Pharmacol. 2016 Apr;89(4):399-406. doi: 10.1124/mol.115.102202. Epub 2016 Jan 14. Mol Pharmacol. 2016. PMID: 26769414 Free PMC article.

5

A clickable neurosteroid photolabel reveals selective Golgi compartmentalization with preferential impact on proximal inhibition.

Jiang X, Shu HJ, Krishnan K, Qian M, Taylor AA, Covey DF, Zorumski CF, Mennerick S. Jiang X, et al. Among authors: qian m. Neuropharmacology. 2016 Sep;108:193-206. doi: 10.1016/j.neuropharm.2016.04.031. Epub 2016 Apr 22. Neuropharmacology. 2016. PMID: 27114255 Free PMC article.

6

Structure-activity studies of non-steroid analogues structurally-related to neuroprotective estrogens.

Qian M, Engler-Chiurazzi EB, Lewis SE, Rath NP, Simpkins JW, Covey DF. Qian M, et al. Org Biomol Chem. 2016 Oct 18;14(41):9790-9805. doi: 10.1039/c6ob01726f. Org Biomol Chem. 2016. PMID: 27714297 Free PMC article.

7

Click Chemistry Reagent for Identification of Sites of Covalent Ligand Incorporation in Integral Membrane Proteins.

Budelier MM, Cheng WW, Bergdoll L, Chen ZW, Abramson J, Krishnan K, Qian M, Covey DF, Janetka JW, Evers AS. Budelier MM, et al. Among authors: qian m. Anal Chem. 2017 Feb 21;89(4):2636-2644. doi: 10.1021/acs.analchem.6b05003. Epub 2017 Feb 9. Anal Chem. 2017. PMID: 28194953 Free PMC article.

8

Visualizing pregnenolone sulfate-like modulators of NMDA receptor function reveals intracellular and plasma-membrane localization.

Chisari M, Wilding TJ, Brunwasser S, Krishnan K, Qian M, Benz A, Huettner JE, Zorumski CF, Covey DF, Mennerick S. Chisari M, et al. Among authors: qian m. Neuropharmacology. 2019 Jan;144:91-103. doi: 10.1016/j.neuropharm.2018.10.015. Epub 2018 Oct 15. Neuropharmacology. 2019. PMID: 30332607 Free PMC article.

9

A Clickable Oxysterol Photolabel Retains NMDA Receptor Activity and Accumulates in Neurons.

Chen DM, Ziolkowski L, Benz A, Qian M, Zorumski CF, Covey DF, Mennerick S. Chen DM, et al. Among authors: qian m. Front Neurosci. 2018 Dec 6;12:923. doi: 10.3389/fnins.2018.00923. eCollection 2018. Front Neurosci. 2018. PMID: 30574068 Free PMC article.

10

Multiple functional neurosteroid binding sites on GABAA receptors.

Chen ZW, Bracamontes JR, Budelier MM, Germann AL, Shin DJ, Kathiresan K, Qian MX, Manion B, Cheng WWL, Reichert DE, Akk G, Covey DF, Evers AS. Chen ZW, et al. Among authors: qian mx. PLoS Biol. 2019 Mar 7;17(3):e3000157. doi: 10.1371/journal.pbio.3000157. eCollection 2019 Mar. PLoS Biol. 2019. PMID: 30845142 Free PMC article.

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