Holtzman DM - Search Results

1

25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.

Wong MY, Lewis M, Doherty JJ, Shi Y, Cashikar AG, Amelianchik A, Tymchuk S, Sullivan PM, Qian M, Covey DF, Petsko GA, Holtzman DM, Paul SM, Luo W. Wong MY, et al. Among authors: holtzman dm. J Neuroinflammation. 2020 Jun 17;17(1):192. doi: 10.1186/s12974-020-01869-3. J Neuroinflammation. 2020. PMID: 32552741 Free PMC article.

2

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease.

Holtzman DM, Bales KR, Wu S, Bhat P, Parsadanian M, Fagan AM, Chang LK, Sun Y, Paul SM. Holtzman DM, et al. J Clin Invest. 1999 Mar;103(6):R15-R21. doi: 10.1172/JCI6179. J Clin Invest. 1999. PMID: 10079115 Free PMC article.

3

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease.

Holtzman DM, Bales KR, Tenkova T, Fagan AM, Parsadanian M, Sartorius LJ, Mackey B, Olney J, McKeel D, Wozniak D, Paul SM. Holtzman DM, et al. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2892-7. doi: 10.1073/pnas.050004797. Proc Natl Acad Sci U S A. 2000. PMID: 10694577 Free PMC article.

4

Apolipoprotein E facilitates neuritic and cerebrovascular plaque formation in an Alzheimer's disease model.

Holtzman DM, Fagan AM, Mackey B, Tenkova T, Sartorius L, Paul SM, Bales K, Ashe KH, Irizarry MC, Hyman BT. Holtzman DM, et al. Ann Neurol. 2000 Jun;47(6):739-47. Ann Neurol. 2000. PMID: 10852539

5

Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E.

Bales KR, Du Y, Holtzman D, Cordell B, Paul SM. Bales KR, et al. Neurobiol Aging. 2000 May-Jun;21(3):427-32; discussion 451-3. doi: 10.1016/s0197-4580(00)00143-3. Neurobiol Aging. 2000. PMID: 10858588 No abstract available.

6

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease.

DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. DeMattos RB, et al. Among authors: holtzman dm. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8850-5. doi: 10.1073/pnas.151261398. Epub 2001 Jul 3. Proc Natl Acad Sci U S A. 2001. PMID: 11438712 Free PMC article.

7

Purification and characterization of astrocyte-secreted apolipoprotein E and J-containing lipoproteins from wild-type and human apoE transgenic mice.

DeMattos RB, Brendza RP, Heuser JE, Kierson M, Cirrito JR, Fryer J, Sullivan PM, Fagan AM, Han X, Holtzman DM. DeMattos RB, et al. Among authors: holtzman dm. Neurochem Int. 2001 Nov-Dec;39(5-6):415-25. doi: 10.1016/s0197-0186(01)00049-3. Neurochem Int. 2001. PMID: 11578777

8

Role of apoE/Abeta interactions in Alzheimer's disease: insights from transgenic mouse models.

Brendza RP, Bales KR, Paul SM, Holtzman DM. Brendza RP, et al. Among authors: holtzman dm. Mol Psychiatry. 2002;7(2):132-5. doi: 10.1038/sj.mp.4001006. Mol Psychiatry. 2002. PMID: 11840304 Review. No abstract available.

9

Brain to plasma amyloid-beta efflux: a measure of brain amyloid burden in a mouse model of Alzheimer's disease.

DeMattos RB, Bales KR, Cummins DJ, Paul SM, Holtzman DM. DeMattos RB, et al. Among authors: holtzman dm. Science. 2002 Mar 22;295(5563):2264-7. doi: 10.1126/science.1067568. Science. 2002. PMID: 11910111

10

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

Dodart JC, Bales KR, Gannon KS, Greene SJ, DeMattos RB, Mathis C, DeLong CA, Wu S, Wu X, Holtzman DM, Paul SM. Dodart JC, et al. Among authors: holtzman dm. Nat Neurosci. 2002 May;5(5):452-7. doi: 10.1038/nn842. Nat Neurosci. 2002. PMID: 11941374

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