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An intrinsic S/G2 checkpoint enforced by ATR.
Saldivar JC, Hamperl S, Bocek MJ, Chung M, Bass TE, Cisneros-Soberanis F, Samejima K, Xie L, Paulson JR, Earnshaw WC, Cortez D, Meyer T, Cimprich KA. Saldivar JC, et al. Among authors: bocek mj. Science. 2018 Aug 24;361(6404):806-810. doi: 10.1126/science.aap9346. Science. 2018. PMID: 30139873 Free PMC article.
R-Loops as Cellular Regulators and Genomic Threats.
Crossley MP, Bocek M, Cimprich KA. Crossley MP, et al. Mol Cell. 2019 Feb 7;73(3):398-411. doi: 10.1016/j.molcel.2019.01.024. Mol Cell. 2019. PMID: 30735654 Free PMC article. Review.
R-loop-derived cytoplasmic RNA-DNA hybrids activate an immune response.
Crossley MP, Song C, Bocek MJ, Choi JH, Kousouros JN, Sathirachinda A, Lin C, Brickner JR, Bai G, Lans H, Vermeulen W, Abu-Remaileh M, Cimprich KA. Crossley MP, et al. Among authors: bocek mj. Nature. 2023 Jan;613(7942):187-194. doi: 10.1038/s41586-022-05545-9. Epub 2022 Dec 21. Nature. 2023. PMID: 36544021 Free PMC article.
11 results