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Allosteric control of hemoglobin S fiber formation by oxygen and its relation to the pathophysiology of sickle cell disease.
Henry ER, Cellmer T, Dunkelberger EB, Metaferia B, Hofrichter J, Li Q, Ostrowski D, Ghirlando R, Louis JM, Moutereau S, Galactéros F, Thein SL, Bartolucci P, Eaton WA. Henry ER, et al. Among authors: hofrichter j. Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15018-15027. doi: 10.1073/pnas.1922004117. Epub 2020 Jun 11. Proc Natl Acad Sci U S A. 2020. PMID: 32527859 Free PMC article.
A tertiary two-state allosteric model for hemoglobin.
Henry ER, Bettati S, Hofrichter J, Eaton WA. Henry ER, et al. Among authors: hofrichter j. Biophys Chem. 2002 Jul 10;98(1-2):149-64. doi: 10.1016/s0301-4622(02)00091-1. Biophys Chem. 2002. PMID: 12128196
Evolution of allosteric models for hemoglobin.
Eaton WA, Henry ER, Hofrichter J, Bettati S, Viappiani C, Mozzarelli A. Eaton WA, et al. Among authors: hofrichter j. IUBMB Life. 2007 Aug-Sep;59(8-9):586-99. doi: 10.1080/15216540701272380. IUBMB Life. 2007. PMID: 17701554 Free article. Review.
Measuring internal friction of an ultrafast-folding protein.
Cellmer T, Henry ER, Hofrichter J, Eaton WA. Cellmer T, et al. Among authors: hofrichter j. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18320-5. doi: 10.1073/pnas.0806154105. Epub 2008 Nov 19. Proc Natl Acad Sci U S A. 2008. PMID: 19020085 Free PMC article.
Kinetic assay shows that increasing red cell volume could be a treatment for sickle cell disease.
Li Q, Henry ER, Hofrichter J, Smith JF, Cellmer T, Dunkelberger EB, Metaferia BB, Jones-Straehle S, Boutom S, Christoph GW, Wakefield TH, Link ME, Staton D, Vass ER, Miller JL, Hsieh MM, Tisdale JF, Eaton WA. Li Q, et al. Among authors: hofrichter j. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):E689-E696. doi: 10.1073/pnas.1619054114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096387 Free PMC article.
Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease.
Metaferia B, Cellmer T, Dunkelberger EB, Li Q, Henry ER, Hofrichter J, Staton D, Hsieh MM, Conrey AK, Tisdale JF, Chatterjee AK, Thein SL, Eaton WA. Metaferia B, et al. Among authors: hofrichter j. Proc Natl Acad Sci U S A. 2022 Oct 4;119(40):e2210779119. doi: 10.1073/pnas.2210779119. Epub 2022 Sep 26. Proc Natl Acad Sci U S A. 2022. PMID: 36161945 Free PMC article.
Sickle cell hemoglobin polymerization.
Eaton WA, Hofrichter J. Eaton WA, et al. Among authors: hofrichter j. Adv Protein Chem. 1990;40:63-279. doi: 10.1016/s0065-3233(08)60287-9. Adv Protein Chem. 1990. PMID: 2195851 Review. No abstract available.
Hemoglobin S gelation and sickle cell disease.
Eaton WA, Hofrichter J. Eaton WA, et al. Among authors: hofrichter j. Blood. 1987 Nov;70(5):1245-66. Blood. 1987. PMID: 3311198 Free article. Review. No abstract available.
114 results