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Page 1
Building global development strategies for cf therapeutics during a transitional cftr modulator era.
Mayer-Hamblett N, van Koningsbruggen-Rietschel S, Nichols DP, VanDevanter DR, Davies JC, Lee T, Durmowicz AG, Ratjen F, Konstan MW, Pearson K, Bell SC, Clancy JP, Taylor-Cousar JL, De Boeck K, Donaldson SH, Downey DG, Flume PA, Drevinek P, Goss CH, Fajac I, Magaret AS, Quon BS, Singleton SM, VanDalfsen JM, Retsch-Bogart GZ. Mayer-Hamblett N, et al. Among authors: downey dg. J Cyst Fibros. 2020 Sep;19(5):677-687. doi: 10.1016/j.jcf.2020.05.011. Epub 2020 Jun 7. J Cyst Fibros. 2020. PMID: 32522463 Free PMC article. Review.
Neutrophils in cystic fibrosis.
Downey DG, Bell SC, Elborn JS. Downey DG, et al. Thorax. 2009 Jan;64(1):81-8. doi: 10.1136/thx.2007.082388. Thorax. 2009. PMID: 19103874 Review.
"Pathogen Eradication" and "Emerging Pathogens": Difficult Definitions in Cystic Fibrosis.
Gilligan PH, Downey DG, Elborn JS, Flume PA, Funk S, Gilpin D, Kidd TJ, McCaughan J, Millar BC, Murphy PG, Rendall JC, Tunney MM, Moore JE. Gilligan PH, et al. Among authors: downey dg. J Clin Microbiol. 2018 Aug 27;56(9):e00193-18. doi: 10.1128/JCM.00193-18. Print 2018 Sep. J Clin Microbiol. 2018. PMID: 29875191 Free PMC article.
Theratyping in cystic fibrosis.
Crawford KJ, Downey DG. Crawford KJ, et al. Among authors: downey dg. Curr Opin Pulm Med. 2018 Nov;24(6):612-617. doi: 10.1097/MCP.0000000000000521. Curr Opin Pulm Med. 2018. PMID: 30124524 Review.
VX-659-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles.
Davies JC, Moskowitz SM, Brown C, Horsley A, Mall MA, McKone EF, Plant BJ, Prais D, Ramsey BW, Taylor-Cousar JL, Tullis E, Uluer A, McKee CM, Robertson S, Shilling RA, Simard C, Van Goor F, Waltz D, Xuan F, Young T, Rowe SM; VX16-659-101 Study Group. Davies JC, et al. N Engl J Med. 2018 Oct 25;379(17):1599-1611. doi: 10.1056/NEJMoa1807119. Epub 2018 Oct 18. N Engl J Med. 2018. PMID: 30334693 Free PMC article. Clinical Trial.
Failure to conceive in women with CF is associated with pancreatic insufficiency and advancing age.
Shteinberg M, Lulu AB, Downey DG, Blumenfeld Z, Rousset-Jablonski C, Perceval M, Colombo A, Stein N, Livnat G, Gur M, Bentur L, Mussaffi H, Blau H, Sarouk I, Dagan A, Kerem E, Aviram M, Picard E, Aliberti S, Álvarez A, Miranda JP, Polverino E, Durieu I, Stuart Elborn J, Cohen-Cymberknoh M. Shteinberg M, et al. Among authors: downey dg. J Cyst Fibros. 2019 Jul;18(4):525-529. doi: 10.1016/j.jcf.2018.10.009. Epub 2018 Oct 23. J Cyst Fibros. 2019. PMID: 30366850 Free article.
Assessment of stability and fluctuations of cultured lower airway bacterial communities in people with cystic fibrosis.
Sherrard LJ, Einarsson GG, Johnston E, O'Neill K, McIlreavey L, McGrath SJ, Gilpin DF, Downey DG, Reid A, McElvaney NG, Boucher RC, Muhlebach MS, Elborn JS, Tunney MM. Sherrard LJ, et al. Among authors: downey dg. J Cyst Fibros. 2019 Nov;18(6):808-816. doi: 10.1016/j.jcf.2019.02.012. Epub 2019 Mar 21. J Cyst Fibros. 2019. PMID: 30905581 Free PMC article.
Tackling bias in clinical trials.
van Koningsbruggen-Rietschel S, Downey DG. van Koningsbruggen-Rietschel S, et al. Among authors: downey dg. J Cyst Fibros. 2019 Jul;18(4):445-446. doi: 10.1016/j.jcf.2019.06.001. J Cyst Fibros. 2019. PMID: 31230796 Free article. No abstract available.
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