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Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein.
Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Lee FE, Nguyen DC, Sanz I, Martinez DR, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Zost SJ, et al. Among authors: lee fe. bioRxiv [Preprint]. 2020 May 13:2020.05.12.091462. doi: 10.1101/2020.05.12.091462. bioRxiv. 2020. Update in: Nat Med. 2020 Sep;26(9):1422-1427. doi: 10.1038/s41591-020-0998-x. PMID: 32511414 Free PMC article. Updated. Preprint.
Dominant extrafollicular B cell responses in severe COVID-19 disease correlate with robust viral-specific antibody production but poor clinical outcomes.
Woodruff M, Ramonell R, Cashman K, Nguyen D, Saini A, Haddad N, Ley A, Kyu S, Howell JC, Ozturk T, Lee S, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam F, Sharma M, Wu H, Le S, Jenks S, Tipton CM, Hu W, Lee FE, Sanz I. Woodruff M, et al. Among authors: lee fe, lee s. medRxiv [Preprint]. 2020 Jun 22:2020.04.29.20083717. doi: 10.1101/2020.04.29.20083717. medRxiv. 2020. Update in: Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z. PMID: 32511635 Free PMC article. Updated. Preprint.
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.
Woodruff MC, Ramonell RP, Nguyen DC, Cashman KS, Saini AS, Haddad NS, Ley AM, Kyu S, Howell JC, Ozturk T, Lee S, Suryadevara N, Case JB, Bugrovsky R, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam FA, Sharma M, Wu HM, Le SN, Jenks SA, Tipton CM, Staitieh B, Daiss JL, Ghosn E, Diamond MS, Carnahan RH, Crowe JE Jr, Hu WT, Lee FE, Sanz I. Woodruff MC, et al. Among authors: lee fe, lee s. Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z. Epub 2020 Oct 7. Nat Immunol. 2020. PMID: 33028979 Free PMC article.
Relaxed peripheral tolerance drives broad de novo autoreactivity in severe COVID-19.
Woodruff MC, Ramonell RP, Saini AS, Haddad NS, Anam FA, Rudolph ME, Bugrovsky R, Hom J, Cashman KS, Nguyen DC, Kyu S, Piazza M, Tipton CM, Jenks SA, Lee FE, Sanz I. Woodruff MC, et al. Among authors: lee fe. medRxiv [Preprint]. 2021 Jul 27:2020.10.21.20216192. doi: 10.1101/2020.10.21.20216192. medRxiv. 2021. Update in: Nature. 2022 Nov;611(7934):139-147. doi: 10.1038/s41586-022-05273-0. PMID: 33106819 Free PMC article. Updated. Preprint.
COVID-19 and plasma cells: Is there long-lived protection?
Nguyen DC, Lamothe PA, Woodruff MC, Saini AS, Faliti CE, Sanz I, Lee FE. Nguyen DC, et al. Among authors: lee fe. Immunol Rev. 2022 Aug;309(1):40-63. doi: 10.1111/imr.13115. Epub 2022 Jul 8. Immunol Rev. 2022. PMID: 35801537 Free PMC article. Review.
The Majority of SARS-CoV-2 Plasma Cells are Excluded from the Bone Marrow Long-Lived Compartment 33 Months after mRNA Vaccination.
Nguyen DC, Hentenaar IT, Morrison-Porter A, Solano D, Haddad NS, Castrillon C, Lamothe PA, Andrews J, Roberts D, Lonial S, Sanz I, Lee FE. Nguyen DC, et al. Among authors: lee fe. medRxiv [Preprint]. 2024 Mar 5:2024.03.02.24303242. doi: 10.1101/2024.03.02.24303242. medRxiv. 2024. Update in: Nat Med. 2024 Sep 27. doi: 10.1038/s41591-024-03278-y. PMID: 38496525 Free PMC article. Updated. Preprint.
138 results