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Small-molecule activation of lysosomal TRP channels ameliorates Duchenne muscular dystrophy in mouse models.
Yu L, Zhang X, Yang Y, Li D, Tang K, Zhao Z, He W, Wang C, Sahoo N, Converso-Baran K, Davis CS, Brooks SV, Bigot A, Calvo R, Martinez NJ, Southall N, Hu X, Marugan J, Ferrer M, Xu H. Yu L, et al. Among authors: bigot a. Sci Adv. 2020 Feb 7;6(6):eaaz2736. doi: 10.1126/sciadv.aaz2736. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32128386 Free PMC article.
De novo revertant fiber formation and therapy testing in a 3D culture model of Duchenne muscular dystrophy skeletal muscle.
Ebrahimi M, Lad H, Fusto A, Tiper Y, Datye A, Nguyen CT, Jacques E, Moyle LA, Nguyen T, Musgrave B, Chávez-Madero C, Bigot A, Chen C, Turner S, Stewart BA, Pegoraro E, Vitiello L, Gilbert PM. Ebrahimi M, et al. Among authors: bigot a. Acta Biomater. 2021 Sep 15;132:227-244. doi: 10.1016/j.actbio.2021.05.020. Epub 2021 May 25. Acta Biomater. 2021. PMID: 34048976
SETDB1 modulates the TGFβ response in Duchenne muscular dystrophy myotubes.
Granados A, Zamperoni M, Rapone R, Moulin M, Boyarchuk E, Bouyioukos C, Del Maestro L, Joliot V, Negroni E, Mohamed M, Piquet S, Bigot A, Le Grand F, Albini S, Ait-Si-Ali S. Granados A, et al. Among authors: bigot a. Sci Adv. 2024 May 3;10(18):eadj8042. doi: 10.1126/sciadv.adj8042. Epub 2024 May 1. Sci Adv. 2024. PMID: 38691608 Free PMC article.
Altered in vitro muscle differentiation in X-linked myopathy with excessive autophagy.
Fernandes SA, Almeida CF, Souza LS, Lazar M, Onofre-Oliveira P, Yamamoto GL, Nogueira L, Tasaki LY, Cardoso RR, Pavanello RCM, Silva HCA, Ferrari MFR, Bigot A, Mouly V, Vainzof M. Fernandes SA, et al. Among authors: bigot a. Dis Model Mech. 2020 Jan 10;13(2):dmm041244. doi: 10.1242/dmm.041244. Dis Model Mech. 2020. PMID: 31826868 Free PMC article.
216 results