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Pancreatic islet-specific engineered Tregs exhibit robust antigen-specific and bystander immune suppression in type 1 diabetes models.
Sci Transl Med. 2022 Oct 5;14(665):eabn1716. doi: 10.1126/scitranslmed.abn1716. Epub 2022 Oct 5.
Sci Transl Med. 2022.
PMID: 36197963
Gene editing to induce FOXP3 expression in human CD4+ T cells leads to a stable regulatory phenotype and function.
Honaker Y, Hubbard N, Xiang Y, Fisher L, Hagin D, Sommer K, Song Y, Yang SJ, Lopez C, Tappen T, Dam EM, Khan I, Hale M, Buckner JH, Scharenberg AM, Torgerson TR, Rawlings DJ.
Honaker Y, et al. Among authors: tappen t.
Sci Transl Med. 2020 Jun 3;12(546):eaay6422. doi: 10.1126/scitranslmed.aay6422.
Sci Transl Med. 2020.
PMID: 32493794
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