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Bone marrow regeneration requires mitochondrial transfer from donor Cx43-expressing hematopoietic progenitors to stroma.
Golan K, Singh AK, Kollet O, Bertagna M, Althoff MJ, Khatib-Massalha E, Petrovich-Kopitman E, Wellendorf AM, Massalha H, Levin-Zaidman S, Dadosh T, Bohan B, V Gawali M, Dasgupta B, Lapidot T, Cancelas JA. Golan K, et al. Among authors: wellendorf am. Blood. 2020 Dec 3;136(23):2607-2619. doi: 10.1182/blood.2020005399. Blood. 2020. PMID: 32929449 Free PMC article.
p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche.
Chang KH, Sengupta A, Nayak RC, Duran A, Lee SJ, Pratt RG, Wellendorf AM, Hill SE, Watkins M, Gonzalez-Nieto D, Aronow BJ, Starczynowski DT, Civitelli R, Diaz-Meco MT, Moscat J, Cancelas JA. Chang KH, et al. Among authors: wellendorf am. Cell Rep. 2014 Dec 24;9(6):2084-97. doi: 10.1016/j.celrep.2014.11.031. Epub 2014 Dec 18. Cell Rep. 2014. PMID: 25533346 Free PMC article.
Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT₂R and cytoskeletal dysregulation.
Chang KH, Nayak RC, Roy S, Perumbeti A, Wellendorf AM, Bezold KY, Pirman M, Hill SE, Starnes J, Loberg A, Zhou X, Inagami T, Zheng Y, Malik P, Cancelas JA. Chang KH, et al. Among authors: wellendorf am. Nat Commun. 2015 Jan 9;6:5914. doi: 10.1038/ncomms6914. Nat Commun. 2015. PMID: 25574809 Free PMC article.
TRAF6 Mediates Basal Activation of NF-κB Necessary for Hematopoietic Stem Cell Homeostasis.
Fang J, Muto T, Kleppe M, Bolanos LC, Hueneman KM, Walker CS, Sampson L, Wellendorf AM, Chetal K, Choi K, Salomonis N, Choi Y, Zheng Y, Cancelas JA, Levine RL, Starczynowski DT. Fang J, et al. Among authors: wellendorf am. Cell Rep. 2018 Jan 30;22(5):1250-1262. doi: 10.1016/j.celrep.2018.01.013. Cell Rep. 2018. PMID: 29386112 Free PMC article.
Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors.
Serrano-Lopez J, Nattamai K, Pease NA, Shephard MS, Wellendorf AM, Sertorio M, Smith EA, Geiger H, Wells SI, Cancelas JA, Privette Vinnedge LM. Serrano-Lopez J, et al. Among authors: wellendorf am. Exp Hematol. 2018 Mar;59:40-50.e3. doi: 10.1016/j.exphem.2017.12.009. Epub 2017 Dec 27. Exp Hematol. 2018. PMID: 29288703 Free PMC article.
Inflammation rapidly recruits mammalian GMP and MDP from bone marrow into regional lymphatics.
Serrano-Lopez J, Hegde S, Kumar S, Serrano J, Fang J, Wellendorf AM, Roche PA, Rangel Y, Carrington LJ, Geiger H, Grimes HL, Luther S, Maillard I, Sanchez-Garcia J, Starczynowski DT, Cancelas JA. Serrano-Lopez J, et al. Among authors: wellendorf am. Elife. 2021 Apr 8;10:e66190. doi: 10.7554/eLife.66190. Elife. 2021. PMID: 33830019 Free PMC article.
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