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Page 1
Light Forge: A Microfluidic DNA Melting-based Tuberculosis Test.
Mbano IM, Mandizvo T, Rogich J, Kunota TTR, Mackenzie JS, Pillay M, Balagaddé FK. Mbano IM, et al. Among authors: mackenzie js. J Appl Lab Med. 2020 May 1;5(3):440-453. doi: 10.1093/jalm/jfaa019. J Appl Lab Med. 2020. PMID: 32445364 Free PMC article.
Hydrogen sulfide stimulates Mycobacterium tuberculosis respiration, growth and pathogenesis.
Saini V, Chinta KC, Reddy VP, Glasgow JN, Stein A, Lamprecht DA, Rahman MA, Mackenzie JS, Truebody BE, Adamson JH, Kunota TTR, Bailey SM, Moellering DR, Lancaster JR Jr, Steyn AJC. Saini V, et al. Among authors: mackenzie js. Nat Commun. 2020 Jan 28;11(1):557. doi: 10.1038/s41467-019-14132-y. Nat Commun. 2020. PMID: 31992699 Free PMC article.
Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis.
Lee BS, Hards K, Engelhart CA, Hasenoehrl EJ, Kalia NP, Mackenzie JS, Sviriaeva E, Chong SMS, Manimekalai MSS, Koh VH, Chan J, Xu J, Alonso S, Miller MJ, Steyn AJC, Grüber G, Schnappinger D, Berney M, Cook GM, Moraski GC, Pethe K. Lee BS, et al. Among authors: mackenzie js. EMBO Mol Med. 2021 Jan 11;13(1):e13207. doi: 10.15252/emmm.202013207. Epub 2020 Dec 7. EMBO Mol Med. 2021. PMID: 33283973 Free PMC article.
Mycobacterium tuberculosis senses host Interferon-γ via the membrane protein MmpL10.
Ahmed M, Mackenzie J, Tezera L, Krause R, Truebody B, Garay-Baquero D, Vallejo A, Govender K, Adamson J, Fisher H, Essex JW, Mansour S, Elkington P, Steyn AJC, Leslie A. Ahmed M, et al. Commun Biol. 2022 Dec 1;5(1):1317. doi: 10.1038/s42003-022-04265-0. Commun Biol. 2022. PMID: 36456824 Free PMC article.
Engineered Mycobacteriophage TM4::GeNL Rapidly Determines Bedaquiline, Pretomanid, Linezolid, Rifampicin, and Clofazimine Sensitivity in Mycobacterium tuberculosis Clinical Isolates.
Rajagopalan S, Rourke AK, Asare E, Kohlerschmidt DJ, Das L, Ngema SL, Mulholland CV, Vilchèze C, Mahalingam V, Moodley S, Truebody B, Mackenzie J, Steyn AJC, Perumal R, Berney M, Larsen MH, O'Donnell MR, Escuyer VE, Jacobs WR Jr. Rajagopalan S, et al. J Infect Dis. 2024 Oct 16:jiae438. doi: 10.1093/infdis/jiae438. Online ahead of print. J Infect Dis. 2024. PMID: 39412357
Identification of Chemical Scaffolds That Inhibit the Mycobacterium tuberculosis Respiratory Complex Succinate Dehydrogenase.
Adolph C, Hards K, Williams ZC, Cheung CY, Keighley LM, Jowsey WJ, Kyte M, Inaoka DK, Kita K, Mackenzie JS, Steyn AJC, Li Z, Yan M, Tian GB, Zhang T, Ding X, Furkert DP, Brimble MA, Hickey AJR, McNeil MB, Cook GM. Adolph C, et al. Among authors: mackenzie js. ACS Infect Dis. 2024 Oct 11;10(10):3496-3515. doi: 10.1021/acsinfecdis.3c00655. Epub 2024 Sep 13. ACS Infect Dis. 2024. PMID: 39268963
251 results