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Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages.
Zheng L, Settle M, Brubaker G, Schmitt D, Hazen SL, Smith JD, Kinter M. Zheng L, et al. Among authors: brubaker g. J Biol Chem. 2005 Jan 7;280(1):38-47. doi: 10.1074/jbc.M407019200. Epub 2004 Oct 21. J Biol Chem. 2005. PMID: 15498770 Free article.
Tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein A-I functional activities.
Peng DQ, Wu Z, Brubaker G, Zheng L, Settle M, Gross E, Kinter M, Hazen SL, Smith JD. Peng DQ, et al. Among authors: brubaker g. J Biol Chem. 2005 Oct 7;280(40):33775-84. doi: 10.1074/jbc.M504092200. Epub 2005 Aug 8. J Biol Chem. 2005. PMID: 16091367 Free article.
We also reported that MPO-mediated chlorination preferentially modifies two of the seven tyrosines in apoAI, and loss of parent peptides containing these residues dose-dependently correlates with loss in ABCA1-mediated cholesterol acceptor activity (Zheng, L., Settle, M., Brub …
We also reported that MPO-mediated chlorination preferentially modifies two of the seven tyrosines in apoAI, and loss of parent peptides con …
65 results