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Model-Based Analysis Reveals a Sustained and Dose-Dependent Acceleration of Wound Healing by VEGF-A mRNA (AZD8601).
Almquist J, Rikard SM, Wågberg M, Bruce AC, Gennemark P, Fritsche-Danielson R, Chien KR, Peirce SM, Hansson K, Lundahl A. Almquist J, et al. Among authors: gennemark p. CPT Pharmacometrics Syst Pharmacol. 2020 Jul;9(7):384-394. doi: 10.1002/psp4.12516. Epub 2020 Jul 5. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 32438492 Free PMC article.
Quantifying and Communicating Uncertainty in Preclinical Human Dose-Prediction.
Sundqvist M, Lundahl A, Någård MB, Bredberg U, Gennemark P. Sundqvist M, et al. Among authors: gennemark p. CPT Pharmacometrics Syst Pharmacol. 2015 Apr;4(4):243-54. doi: 10.1002/psp4.32. Epub 2015 Apr 16. CPT Pharmacometrics Syst Pharmacol. 2015. PMID: 26225248 Free PMC article.
Unraveling the pharmacokinetic interaction of ticagrelor and MEDI2452 (Ticagrelor antidote) by mathematical modeling.
Almquist J, Penney M, Pehrsson S, Sandinge AS, Janefeldt A, Maqbool S, Madalli S, Goodman J, Nylander S, Gennemark P. Almquist J, et al. Among authors: gennemark p. CPT Pharmacometrics Syst Pharmacol. 2016 Jun;5(6):313-23. doi: 10.1002/psp4.12089. Epub 2016 Jun 16. CPT Pharmacometrics Syst Pharmacol. 2016. PMID: 27310493 Free PMC article.
Mathematical Model Predicts that Acceleration of Diabetic Wound Healing is Dependent on Spatial Distribution of VEGF-A mRNA (AZD8601).
Rikard SM, Myers PJ, Almquist J, Gennemark P, Bruce AC, Wågberg M, Fritsche-Danielson R, Hansson KM, Lazzara MJ, Peirce SM. Rikard SM, et al. Among authors: gennemark p. Cell Mol Bioeng. 2021 Jun 15;14(4):321-338. doi: 10.1007/s12195-021-00678-9. eCollection 2021 Aug. Cell Mol Bioeng. 2021. PMID: 34290839 Free PMC article.
A case-study of model-informed drug development of a novel PCSK9 anti sense oligonucleotide. Part 1: First time in man to phase II.
Knöchel J, Nilsson C, Carlsson B, Wernevik L, Hofherr A, Gennemark P, Jansson-Löfmark R, Isaksson R, Rydén-Bergsten T, Hamrén B, Rekić D. Knöchel J, et al. Among authors: gennemark p. CPT Pharmacometrics Syst Pharmacol. 2022 Dec;11(12):1569-1577. doi: 10.1002/psp4.12866. Epub 2022 Oct 1. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 36126230 Free PMC article. Clinical Trial.
51 results