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Page 1
Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.
Romanelli A, Stazi G, Fioravanti R, Zwergel C, Di Bello E, Pomella S, Perrone C, Battistelli C, Strippoli R, Tripodi M, Del Bufalo D, Rota R, Trisciuoglio D, Mai A, Valente S. Romanelli A, et al. Among authors: di bello e. ACS Med Chem Lett. 2020 Mar 19;11(5):977-983. doi: 10.1021/acsmedchemlett.0c00014. eCollection 2020 May 14. ACS Med Chem Lett. 2020. PMID: 32435414 Free PMC article.
Tranylcypromine-Based LSD1 Inhibitors: Structure-Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation.
Fioravanti R, Romanelli A, Mautone N, Di Bello E, Rovere A, Corinti D, Zwergel C, Valente S, Rotili D, Botrugno OA, Dessanti P, Vultaggio S, Vianello P, Cappa A, Binda C, Mattevi A, Minucci S, Mercurio C, Varasi M, Mai A. Fioravanti R, et al. Among authors: di bello e. ChemMedChem. 2020 Apr 3;15(7):643-658. doi: 10.1002/cmdc.201900730. Epub 2020 Feb 14. ChemMedChem. 2020. PMID: 32003940 Free PMC article.
Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity.
Fioravanti R, Rodriguez V, Caroli J, Chianese U, Benedetti R, Di Bello E, Noce B, Zwergel C, Corinti D, Viña D, Altucci L, Mattevi A, Valente S, Mai A. Fioravanti R, et al. Among authors: di bello e. J Enzyme Inhib Med Chem. 2022 Dec;37(1):973-985. doi: 10.1080/14756366.2022.2052869. J Enzyme Inhib Med Chem. 2022. PMID: 35317680 Free PMC article.
Novel Targeting of DNA Methyltransferase Activity Inhibits Ewing Sarcoma Cell Proliferation and Enhances Tumor Cell Sensitivity to DNA Damaging Drugs by Activating the DNA Damage Response.
Cristalli C, Manara MC, Valente S, Pellegrini E, Bavelloni A, De Feo A, Blalock W, Di Bello E, Piñeyro D, Merkel A, Esteller M, Tirado OM, Mai A, Scotlandi K. Cristalli C, et al. Among authors: di bello e. Front Endocrinol (Lausanne). 2022 May 31;13:876602. doi: 10.3389/fendo.2022.876602. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 35712255 Free PMC article.
Effects of Structurally Different HDAC Inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni.
Di Bello E, Noce B, Fioravanti R, Zwergel C, Valente S, Rotili D, Fianco G, Trisciuoglio D, Mourão MM, Sales P Jr, Lamotte S, Prina E, Späth GF, Häberli C, Keiser J, Mai A. Di Bello E, et al. ACS Infect Dis. 2022 Jul 8;8(7):1356-1366. doi: 10.1021/acsinfecdis.2c00232. Epub 2022 Jun 22. ACS Infect Dis. 2022. PMID: 35732073 Free PMC article.
Seleno-vs. thioether triazine derivatives in search for new anticancer agents overcoming multidrug resistance in lymphoma.
Ali W, Garbo S, Kincses A, Nové M, Spengler G, Di Bello E, Honkisz-Orzechowska E, Karcz T, Szymańska E, Żesławska E, Starek M, Dąbrowska M, Nitek W, Kucwaj-Brysz K, Pyka P, Fioravanti R, Jacob C, Battistelli C, Zwergel C, Handzlik J. Ali W, et al. Among authors: di bello e. Eur J Med Chem. 2022 Dec 5;243:114761. doi: 10.1016/j.ejmech.2022.114761. Epub 2022 Sep 19. Eur J Med Chem. 2022. PMID: 36179403
Potent and Specific Activators for Mitochondrial Sirtuins Sirt3 and Sirt5.
Suenkel B, Valente S, Zwergel C, Weiss S, Di Bello E, Fioravanti R, Aventaggiato M, Amorim JA, Garg N, Kumar S, Lombard DB, Hu T, Singh PK, Tafani M, Palmeira CM, Sinclair D, Mai A, Steegborn C. Suenkel B, et al. Among authors: di bello e. J Med Chem. 2022 Oct 27;65(20):14015-14031. doi: 10.1021/acs.jmedchem.2c01215. Epub 2022 Oct 13. J Med Chem. 2022. PMID: 36228194 Free PMC article.
15 results