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TET1 promotes growth of T-cell acute lymphoblastic leukemia and can be antagonized via PARP inhibition.
Bamezai S, Demir D, Pulikkottil AJ, Ciccarone F, Fischbein E, Sinha A, Borga C, Te Kronnie G, Meyer LH, Mohr F, Götze M, Caiafa P, Debatin KM, Döhner K, Döhner H, González-Menéndez I, Quintanilla-Fend L, Herold T, Jeremias I, Feuring-Buske M, Buske C, Rawat VPS. Bamezai S, et al. Among authors: feuring buske m. Leukemia. 2021 Feb;35(2):389-403. doi: 10.1038/s41375-020-0864-3. Epub 2020 May 15. Leukemia. 2021. PMID: 32409690
MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML.
Vegi NM, Klappacher J, Oswald F, Mulaw MA, Mandoli A, Thiel VN, Bamezai S, Feder K, Martens JHA, Rawat VPS, Mandal T, Quintanilla-Martinez L, Spiekermann K, Hiddemann W, Döhner K, Döhner H, Stunnenberg HG, Feuring-Buske M, Buske C. Vegi NM, et al. Cell Rep. 2016 Jul 12;16(2):498-507. doi: 10.1016/j.celrep.2016.05.094. Epub 2016 Jun 23. Cell Rep. 2016. PMID: 27346355 Free article.
VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice.
Gentner E, Vegi NM, Mulaw MA, Mandal T, Bamezai S, Claus R, Tasdogan A, Quintanilla-Martinez L, Grunenberg A, Döhner K, Döhner H, Bullinger L, Haferlach T, Buske C, Rawat VP, Feuring-Buske M. Gentner E, et al. Oncotarget. 2016 Dec 27;7(52):86889-86901. doi: 10.18632/oncotarget.13563. Oncotarget. 2016. PMID: 27888632 Free PMC article.
The microRNA miR-196b acts as a tumor suppressor in Cdx2-driven acute myeloid leukemia.
Rawat VPS, Götze M, Rasalkar A, Vegi NM, Ihme S, Thoene S, Pastore A, Bararia D, Döhner H, Döhner K, Feuring-Buske M, Quintanilla-Fend L, Buske C. Rawat VPS, et al. Among authors: feuring buske m. Haematologica. 2020 Jun;105(6):e285-e289. doi: 10.3324/haematol.2019.223297. Epub 2019 Sep 26. Haematologica. 2020. PMID: 31558674 Free PMC article. No abstract available.
The ParaHox gene Cdx4 induces acute erythroid leukemia in mice.
Thoene S, Mandal T, Vegi NM, Quintanilla-Martinez L, Rösler R, Wiese S, Metzeler KH, Herold T, Haferlach T, Döhner K, Döhner H, Schwarzmüller L, Klingmüller U, Buske C, Rawat VPS, Feuring-Buske M. Thoene S, et al. Among authors: feuring buske m. Blood Adv. 2019 Nov 26;3(22):3729-3739. doi: 10.1182/bloodadvances.2019000761. Blood Adv. 2019. PMID: 31770439 Free PMC article.
The leukemogenicity of Hoxa9 depends on alternative splicing.
Stadler CR, Vegi N, Mulaw MA, Edmaier KE, Rawat VP, Dolnik A, Bullinger L, Heilmeier B, Quintanilla-Fend L, Spiekermann K, Hiddemann W, Döhner K, Döhner H, Feuring-Buske M, Buske C. Stadler CR, et al. Leukemia. 2014 Sep;28(9):1838-43. doi: 10.1038/leu.2014.74. Epub 2014 Feb 18. Leukemia. 2014. PMID: 24535405
81 results