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Aptamer-Based Proteomic Platform Identifies Novel Protein Predictors of Incident Heart Failure and Echocardiographic Traits.
Nayor M, Short MI, Rasheed H, Lin H, Jonasson C, Yang Q, Hveem K, Felix JF, Morrison AC, Wild PS, Morley MP, Cappola TP, Benson MD; CHARGE-Heart Failure Working Group; CHARGE-EchoGen Consortium; Ngo D, Sinha S, Keyes MJ, Shen D, Wang TJ, Larson MG, Brumpton BM, Gerszten RE, Omland T, Vasan RS. Nayor M, et al. Among authors: sinha s. Circ Heart Fail. 2020 May;13(5):e006749. doi: 10.1161/CIRCHEARTFAILURE.119.006749. Epub 2020 May 15. Circ Heart Fail. 2020. PMID: 32408813 Free PMC article.
Genetic Architecture of the Cardiovascular Risk Proteome.
Benson MD, Yang Q, Ngo D, Zhu Y, Shen D, Farrell LA, Sinha S, Keyes MJ, Vasan RS, Larson MG, Smith JG, Wang TJ, Gerszten RE. Benson MD, et al. Among authors: sinha s. Circulation. 2018 Mar 13;137(11):1158-1172. doi: 10.1161/CIRCULATIONAHA.117.029536. Epub 2017 Dec 19. Circulation. 2018. PMID: 29258991 Free PMC article.
Profiling of the plasma proteome across different stages of human heart failure.
Egerstedt A, Berntsson J, Smith ML, Gidlöf O, Nilsson R, Benson M, Wells QS, Celik S, Lejonberg C, Farrell L, Sinha S, Shen D, Lundgren J, Rådegran G, Ngo D, Engström G, Yang Q, Wang TJ, Gerszten RE, Smith JG. Egerstedt A, et al. Among authors: sinha s. Nat Commun. 2019 Dec 20;10(1):5830. doi: 10.1038/s41467-019-13306-y. Nat Commun. 2019. PMID: 31862877 Free PMC article.
Multiomic Profiling in Black and White Populations Reveals Novel Candidate Pathways in Left Ventricular Hypertrophy and Incident Heart Failure Specific to Black Adults.
Katz DH, Tahir UA, Ngo D, Benson MD, Gao Y, Shi X, Nayor M, Keyes MJ, Larson MG, Hall ME, Correa A, Sinha S, Shen D, Herzig M, Yang Q, Robbins JM, Chen ZZ, Cruz DE, Peterson B, Vasan RS, Wang TJ, Wilson JG, Gerszten RE. Katz DH, et al. Among authors: sinha s. Circ Genom Precis Med. 2021 Jun;14(3):e003191. doi: 10.1161/CIRCGEN.120.003191. Epub 2021 May 21. Circ Genom Precis Med. 2021. PMID: 34019435 Free PMC article. Clinical Trial.
Circulating testican-2 is a podocyte-derived marker of kidney health.
Ngo D, Wen D, Gao Y, Keyes MJ, Drury ER, Katz DH, Benson MD, Sinha S, Shen D, Farrell LA, Peterson BD, Friedman DJ, Elmariah S, Young BA, Smith JG, Yang Q, Vasan RS, Larson MG, Correa A, Humphreys BD, Wang TJ, Pollak MR, Wilson JG, Gerszten RE, Rhee EP. Ngo D, et al. Among authors: sinha s. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):25026-25035. doi: 10.1073/pnas.2009606117. Epub 2020 Sep 21. Proc Natl Acad Sci U S A. 2020. PMID: 32958645 Free PMC article.
Proteomic profiling reveals biomarkers and pathways in type 2 diabetes risk.
Ngo D, Benson MD, Long JZ, Chen ZZ, Wang R, Nath AK, Keyes MJ, Shen D, Sinha S, Kuhn E, Morningstar JE, Shi X, Peterson BD, Chan C, Katz DH, Tahir UA, Farrell LA, Melander O, Mosley JD, Carr SA, Vasan RS, Larson MG, Smith JG, Wang TJ, Yang Q, Gerszten RE. Ngo D, et al. Among authors: sinha s. JCI Insight. 2021 Mar 8;6(5):e144392. doi: 10.1172/jci.insight.144392. JCI Insight. 2021. PMID: 33591955 Free PMC article.
Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease.
Katz DH, Tahir UA, Bick AG, Pampana A, Ngo D, Benson MD, Yu Z, Robbins JM, Chen ZZ, Cruz DE, Deng S, Farrell L, Sinha S, Schmaier AA, Shen D, Gao Y, Hall ME, Correa A, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Yao J, Ida Chen YD, Manichaikul AW, Jain D, Bouchard C, Sarzynski MA, Rich SS, Rotter JI, Wang TJ, Wilson JG, Natarajan P, Gerszten RE; National Heart, Lung, and Blood Institute TOPMed (Trans-Omics for Precision Medicine) Consortium†. Katz DH, et al. Among authors: sinha s. Circulation. 2022 Feb;145(5):357-370. doi: 10.1161/CIRCULATIONAHA.121.055117. Epub 2021 Nov 24. Circulation. 2022. PMID: 34814699 Free PMC article.
Metabolic Profiling of Right Ventricular-Pulmonary Vascular Function Reveals Circulating Biomarkers of Pulmonary Hypertension.
Lewis GD, Ngo D, Hemnes AR, Farrell L, Domos C, Pappagianopoulos PP, Dhakal BP, Souza A, Shi X, Pugh ME, Beloiartsev A, Sinha S, Clish CB, Gerszten RE. Lewis GD, et al. Among authors: sinha s. J Am Coll Cardiol. 2016 Jan 19;67(2):174-189. doi: 10.1016/j.jacc.2015.10.072. J Am Coll Cardiol. 2016. PMID: 26791065 Free PMC article.
6,779 results