Sloop KW - Search Results

1

How May GIP Enhance the Therapeutic Efficacy of GLP-1?

Samms RJ, Coghlan MP, Sloop KW. Samms RJ, et al. Among authors: sloop kw. Trends Endocrinol Metab. 2020 Jun;31(6):410-421. doi: 10.1016/j.tem.2020.02.006. Epub 2020 Mar 16. Trends Endocrinol Metab. 2020. PMID: 32396843 Free article. Review.

2

Glucagon as a target for the treatment of Type 2 diabetes.

Sloop KW, Michael MD, Moyers JS. Sloop KW, et al. Expert Opin Ther Targets. 2005 Jun;9(3):593-600. doi: 10.1517/14728222.9.3.593. Expert Opin Ther Targets. 2005. PMID: 15948676 Review.

3

Novel small molecule glucagon-like peptide-1 receptor agonist stimulates insulin secretion in rodents and from human islets.

Sloop KW, Willard FS, Brenner MB, Ficorilli J, Valasek K, Showalter AD, Farb TB, Cao JX, Cox AL, Michael MD, Gutierrez Sanfeliciano SM, Tebbe MJ, Coghlan MJ. Sloop KW, et al. Diabetes. 2010 Dec;59(12):3099-107. doi: 10.2337/db10-0689. Epub 2010 Sep 7. Diabetes. 2010. PMID: 20823098 Free PMC article.

4

Small molecule drug discovery at the glucagon-like peptide-1 receptor.

Willard FS, Bueno AB, Sloop KW. Willard FS, et al. Among authors: sloop kw. Exp Diabetes Res. 2012;2012:709893. doi: 10.1155/2012/709893. Epub 2012 Feb 23. Exp Diabetes Res. 2012. PMID: 22611375 Free PMC article. Review.

5

Small molecule allosteric modulation of the glucagon-like Peptide-1 receptor enhances the insulinotropic effect of oxyntomodulin.

Willard FS, Wootten D, Showalter AD, Savage EE, Ficorilli J, Farb TB, Bokvist K, Alsina-Fernandez J, Furness SG, Christopoulos A, Sexton PM, Sloop KW. Willard FS, et al. Among authors: sloop kw. Mol Pharmacol. 2012 Dec;82(6):1066-73. doi: 10.1124/mol.112.080432. Epub 2012 Aug 28. Mol Pharmacol. 2012. PMID: 22930710

6

A novel humanized GLP-1 receptor model enables both affinity purification and Cre-LoxP deletion of the receptor.

Jun LS, Showalter AD, Ali N, Dai F, Ma W, Coskun T, Ficorilli JV, Wheeler MB, Michael MD, Sloop KW. Jun LS, et al. Among authors: sloop kw. PLoS One. 2014 Apr 2;9(4):e93746. doi: 10.1371/journal.pone.0093746. eCollection 2014. PLoS One. 2014. PMID: 24695667 Free PMC article.

7

Absence of glucagon and insulin action reveals a role for the GLP-1 receptor in endogenous glucose production.

Jun LS, Millican RL, Hawkins ED, Konkol DL, Showalter AD, Christe ME, Michael MD, Sloop KW. Jun LS, et al. Among authors: sloop kw. Diabetes. 2015 Mar;64(3):819-27. doi: 10.2337/db14-1052. Epub 2014 Oct 6. Diabetes. 2015. PMID: 25288673

8

β-Cell Glucagon-Like Peptide-1 Receptor Contributes to Improved Glucose Tolerance After Vertical Sleeve Gastrectomy.

Garibay D, McGavigan AK, Lee SA, Ficorilli JV, Cox AL, Michael MD, Sloop KW, Cummings BP. Garibay D, et al. Among authors: sloop kw. Endocrinology. 2016 Sep;157(9):3405-9. doi: 10.1210/en.2016-1302. Epub 2016 Aug 8. Endocrinology. 2016. PMID: 27501183 Free PMC article.

9

Insulin and Glucagon: Partners for Life.

Holst JJ, Holland W, Gromada J, Lee Y, Unger RH, Yan H, Sloop KW, Kieffer TJ, Damond N, Herrera PL. Holst JJ, et al. Among authors: sloop kw. Endocrinology. 2017 Apr 1;158(4):696-701. doi: 10.1210/en.2016-1748. Endocrinology. 2017. PMID: 28323959 Free PMC article. Review.

10

Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery.

Briere DA, Bueno AB, Gunn EJ, Michael MD, Sloop KW. Briere DA, et al. Among authors: sloop kw. Diabetes. 2018 Feb;67(2):309-320. doi: 10.2337/db17-0607. Epub 2017 Dec 4. Diabetes. 2018. PMID: 29203510

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