Khacho M - Search Results

1

MCL-1^Matrix maintains neuronal survival by enhancing mitochondrial integrity and bioenergetic capacity under stress conditions.

Anilkumar U, Khacho M, Cuillerier A, Harris R, Patten DA, Bilen M, Iqbal MA, Guo DY, Trudeau LE, Park DS, Harper ME, Burelle Y, Slack RS. Anilkumar U, et al. Among authors: khacho m. Cell Death Dis. 2020 May 5;11(5):321. doi: 10.1038/s41419-020-2498-9. Cell Death Dis. 2020. PMID: 32371858 Free PMC article.

2

LKB1-regulated adaptive mechanisms are essential for neuronal survival following mitochondrial dysfunction.

Germain M, Nguyen AP, Khacho M, Patten DA, Screaton RA, Park DS, Slack RS. Germain M, et al. Among authors: khacho m. Hum Mol Genet. 2013 Mar 1;22(5):952-62. doi: 10.1093/hmg/dds500. Epub 2012 Nov 27. Hum Mol Genet. 2013. PMID: 23187960

3

Acidosis overrides oxygen deprivation to maintain mitochondrial function and cell survival.

Khacho M, Tarabay M, Patten D, Khacho P, MacLaurin JG, Guadagno J, Bergeron R, Cregan SP, Harper ME, Park DS, Slack RS. Khacho M, et al. Among authors: khacho p. Nat Commun. 2014 Apr 1;5:3550. doi: 10.1038/ncomms4550. Nat Commun. 2014. PMID: 24686499 Free PMC article.

4

OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand.

Patten DA, Wong J, Khacho M, Soubannier V, Mailloux RJ, Pilon-Larose K, MacLaurin JG, Park DS, McBride HM, Trinkle-Mulcahy L, Harper ME, Germain M, Slack RS. Patten DA, et al. Among authors: khacho m. EMBO J. 2014 Nov 18;33(22):2676-91. doi: 10.15252/embj.201488349. Epub 2014 Oct 8. EMBO J. 2014. PMID: 25298396 Free PMC article.

5

Mitochondrial Dynamics Impacts Stem Cell Identity and Fate Decisions by Regulating a Nuclear Transcriptional Program.

Khacho M, Clark A, Svoboda DS, Azzi J, MacLaurin JG, Meghaizel C, Sesaki H, Lagace DC, Germain M, Harper ME, Park DS, Slack RS. Khacho M, et al. Cell Stem Cell. 2016 Aug 4;19(2):232-247. doi: 10.1016/j.stem.2016.04.015. Epub 2016 May 26. Cell Stem Cell. 2016. PMID: 27237737 Free article.

6

Mitochondrial dysfunction underlies cognitive defects as a result of neural stem cell depletion and impaired neurogenesis.

Khacho M, Clark A, Svoboda DS, MacLaurin JG, Lagace DC, Park DS, Slack RS. Khacho M, et al. Hum Mol Genet. 2017 Sep 1;26(17):3327-3341. doi: 10.1093/hmg/ddx217. Hum Mol Genet. 2017. PMID: 28595361 Free PMC article.

7

Mitochondrial dynamics in the regulation of neurogenesis: From development to the adult brain.

Khacho M, Slack RS. Khacho M, et al. Dev Dyn. 2018 Jan;247(1):47-53. doi: 10.1002/dvdy.24538. Epub 2017 Jul 13. Dev Dyn. 2018. PMID: 28643345 Free article. Review.

8

Mitochondrial and Reactive Oxygen Species Signaling Coordinate Stem Cell Fate Decisions and Life Long Maintenance.

Khacho M, Slack RS. Khacho M, et al. Antioxid Redox Signal. 2018 Apr 10;28(11):1090-1101. doi: 10.1089/ars.2017.7228. Epub 2017 Jul 31. Antioxid Redox Signal. 2018. PMID: 28657337

9

Mitochondrial activity in the regulation of stem cell self-renewal and differentiation.

Khacho M, Slack RS. Khacho M, et al. Curr Opin Cell Biol. 2017 Dec;49:1-8. doi: 10.1016/j.ceb.2017.11.003. Epub 2017 Nov 22. Curr Opin Cell Biol. 2017. PMID: 29175320 Review.

10

Mitochondria as central regulators of neural stem cell fate and cognitive function.

Khacho M, Harris R, Slack RS. Khacho M, et al. Nat Rev Neurosci. 2019 Jan;20(1):34-48. doi: 10.1038/s41583-018-0091-3. Nat Rev Neurosci. 2019. PMID: 30464208 Review.

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