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High-Resolution Structure of ClpC1-Rufomycin and Ligand Binding Studies Provide a Framework to Design and Optimize Anti-Tuberculosis Leads.
Wolf NM, Lee H, Choules MP, Pauli GF, Phansalkar R, Anderson JR, Gao W, Ren J, Santarsiero BD, Lee H, Cheng J, Jin YY, Ho NA, Duc NM, Suh JW, Abad-Zapatero C, Cho S. Wolf NM, et al. ACS Infect Dis. 2019 Jun 14;5(6):829-840. doi: 10.1021/acsinfecdis.8b00276. Epub 2019 May 3. ACS Infect Dis. 2019. PMID: 30990022 Free PMC article.
Antimycobacterial Rufomycin Analogues from Streptomyces atratus Strain MJM3502.
Zhou B, Shetye G, Yu Y, Santarsiero BD, Klein LL, Abad-Zapatero C, Wolf NM, Cheng J, Jin Y, Lee H, Suh JW, Lee H, Bisson J, McAlpine JB, Chen SN, Cho SH, Franzblau SG, Pauli GF. Zhou B, et al. Among authors: wolf nm. J Nat Prod. 2020 Mar 27;83(3):657-667. doi: 10.1021/acs.jnatprod.9b01095. Epub 2020 Feb 7. J Nat Prod. 2020. PMID: 32031795 Free PMC article.
Rufomycin Targets ClpC1 Proteolysis in Mycobacterium tuberculosis and M. abscessus.
Choules MP, Wolf NM, Lee H, Anderson JR, Grzelak EM, Wang Y, Ma R, Gao W, McAlpine JB, Jin YY, Cheng J, Lee H, Suh JW, Duc NM, Paik S, Choe JH, Jo EK, Chang CL, Lee JS, Jaki BU, Pauli GF, Franzblau SG, Cho S. Choules MP, et al. Among authors: wolf nm. Antimicrob Agents Chemother. 2019 Feb 26;63(3):e02204-18. doi: 10.1128/AAC.02204-18. Print 2019 Mar. Antimicrob Agents Chemother. 2019. PMID: 30602512 Free PMC article.
Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization.
Bondoc JMG, Gutka HJ, Almutairi MM, Patwell R, Rutter MW, Wolf NM, Samudrala R, Mehboob S, Movahedzadeh F. Bondoc JMG, et al. Among authors: wolf nm. Acta Crystallogr F Struct Biol Commun. 2019 Oct 1;75(Pt 10):646-651. doi: 10.1107/S2053230X19012652. Epub 2019 Sep 24. Acta Crystallogr F Struct Biol Commun. 2019. PMID: 31584013 Free PMC article.
60 results