Heikura T - Search Results

1

Development of Large-Scale Downstream Processing for Lentiviral Vectors.

Valkama AJ, Oruetxebarria I, Lipponen EM, Leinonen HM, Käyhty P, Hynynen H, Turkki V, Malinen J, Miinalainen T, Heikura T, Parker NR, Ylä-Herttuala S, Lesch HP. Valkama AJ, et al. Among authors: heikura t. Mol Ther Methods Clin Dev. 2020 Mar 30;17:717-730. doi: 10.1016/j.omtm.2020.03.025. eCollection 2020 Jun 12. Mol Ther Methods Clin Dev. 2020. PMID: 32346549 Free PMC article.

2

Benchmarking of Scale-X Bioreactor System in Lentiviral and Adenoviral Vector Production.

Leinonen HM, Lepola S, Lipponen EM, Heikura T, Koponen T, Parker N, Ylä-Herttuala S, Lesch HP. Leinonen HM, et al. Among authors: heikura t. Hum Gene Ther. 2020 Mar;31(5-6):376-384. doi: 10.1089/hum.2019.247. Hum Gene Ther. 2020. PMID: 32075423 Free PMC article.

3

Optimization of lentiviral vector production for scale-up in fixed-bed bioreactor.

Valkama AJ, Leinonen HM, Lipponen EM, Turkki V, Malinen J, Heikura T, Ylä-Herttuala S, Lesch HP. Valkama AJ, et al. Among authors: heikura t. Gene Ther. 2018 Jan;25(1):39-46. doi: 10.1038/gt.2017.91. Epub 2017 Oct 5. Gene Ther. 2018. PMID: 29345252 Free PMC article.

4

Lentiviral interferon: A novel method for gene therapy in bladder cancer.

Mokkapati S, Narayan VM, Manyam GC, Lim AH, Duplisea JJ, Kokorovic A, Miest TS, Mitra AP, Plote D, Anand SS, Metcalfe MJ, Dunner K Jr, Johnson BA, Czerniak BA, Nieminen T, Heikura T, Yla-Herttuala S, Parker NR, Schluns KS, McConkey DJ, Dinney CP. Mokkapati S, et al. Among authors: heikura t. Mol Ther Oncolytics. 2022 Jun 10;26:141-157. doi: 10.1016/j.omto.2022.06.005. eCollection 2022 Sep 15. Mol Ther Oncolytics. 2022. PMID: 35847448 Free PMC article.

5

Baculovirus-mediated vascular endothelial growth factor-D(ΔNΔC) gene transfer induces angiogenesis in rabbit skeletal muscle.

Heikura T, Nieminen T, Roschier MM, Karvinen H, Kaikkonen MU, Mähönen AJ, Lesch HP, Rissanen TT, Laitinen OH, Airenne KJ, Ylä-Herttuala S. Heikura T, et al. J Gene Med. 2012 Jan;14(1):35-43. doi: 10.1002/jgm.1637. J Gene Med. 2012. PMID: 22162149

6

Sleeping Beauty Transposon Vectors in Liver-directed Gene Delivery of LDLR and VLDLR for Gene Therapy of Familial Hypercholesterolemia.

Turunen TA, Kurkipuro J, Heikura T, Vuorio T, Hytönen E, Izsvák Z, Ylä-Herttuala S. Turunen TA, et al. Among authors: heikura t. Mol Ther. 2016 Mar;24(3):620-35. doi: 10.1038/mt.2015.221. Epub 2015 Dec 16. Mol Ther. 2016. PMID: 26670130 Free PMC article.

7

Comparison of Efficiency and Function of Vascular Endothelial Growth Factor Adenovirus Vectors in Endothelial Cells for Gene Therapy of Placental Insufficiency.

Rossi C, Lees M, Mehta V, Heikura T, Martin J, Zachary I, Spencer R, Peebles DM, Shaw R, Karhinen M, Yla-Herttuala S, David AL. Rossi C, et al. Among authors: heikura t. Hum Gene Ther. 2020 Nov;31(21-22):1190-1202. doi: 10.1089/hum.2020.006. Hum Gene Ther. 2020. PMID: 32988220 Free PMC article.

8

Preclinical safety, toxicology, and biodistribution study of adenoviral gene therapy with sVEGFR-2 and sVEGFR-3 combined with chemotherapy for ovarian cancer.

Tuppurainen L, Sallinen H, Kokki E, Koponen J, Anttila M, Pulkkinen K, Heikura T, Toivanen P, Hämäläinen K, Kosma VM, Heinonen S, Alitalo K, Ylä-Herttuala S. Tuppurainen L, et al. Among authors: heikura t. Hum Gene Ther Clin Dev. 2013 Mar;24(1):29-37. doi: 10.1089/humc.2013.006. Epub 2013 Apr 3. Hum Gene Ther Clin Dev. 2013. PMID: 23692381

9

Efficacy and Safety of Clinical-Grade Human Vascular Endothelial Growth Factor-D^ΔNΔC Gene Therapy Containing Residual Replication-Competent Adenoviruses.

Leikas AJ, Laham-Karam N, Agtereek E, Peltonen HM, Selander T, Korpisalo P, Holappa L, Hartikainen JEK, Heikura T, Ylä-Herttuala S. Leikas AJ, et al. Among authors: heikura t. Hum Gene Ther. 2021 Jul;32(13-14):761-770. doi: 10.1089/hum.2020.299. Epub 2021 Mar 4. Hum Gene Ther. 2021. PMID: 33371775

10

Beyond endothelial cells: Vascular endothelial growth factors in heart, vascular anomalies and placenta.

Laakkonen JP, Lähteenvuo J, Jauhiainen S, Heikura T, Ylä-Herttuala S. Laakkonen JP, et al. Among authors: heikura t. Vascul Pharmacol. 2019 Jan;112:91-101. doi: 10.1016/j.vph.2018.10.005. Epub 2018 Oct 17. Vascul Pharmacol. 2019. PMID: 30342234 Free article. Review.

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