Wells JA - Search Results

1

Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer.

Moroz A, Wang YH, Sharib JM, Wei J, Zhao N, Huang Y, Chen Z, Martinko AJ, Zhuo J, Lim SA, Zhang LH, Seo Y, Carlin S, Leung KK, Collisson EA, Kirkwood KS, Wells JA, Evans MJ. Moroz A, et al. Among authors: wells ja. Clin Cancer Res. 2020 Jul 15;26(14):3608-3615. doi: 10.1158/1078-0432.CCR-20-0268. Epub 2020 Apr 27. Clin Cancer Res. 2020. PMID: 32341034 Free PMC article.

2

Human antibody-based chemically induced dimerizers for cell therapeutic applications.

Hill ZB, Martinko AJ, Nguyen DP, Wells JA. Hill ZB, et al. Among authors: wells ja. Nat Chem Biol. 2018 Feb;14(2):112-117. doi: 10.1038/nchembio.2529. Epub 2017 Dec 4. Nat Chem Biol. 2018. PMID: 29200207 Free PMC article.

3

Targeting RAS-driven human cancer cells with antibodies to upregulated and essential cell-surface proteins.

Martinko AJ, Truillet C, Julien O, Diaz JE, Horlbeck MA, Whiteley G, Blonder J, Weissman JS, Bandyopadhyay S, Evans MJ, Wells JA. Martinko AJ, et al. Among authors: wells ja. Elife. 2018 Jan 23;7:e31098. doi: 10.7554/eLife.31098. Elife. 2018. PMID: 29359686 Free PMC article.

4

Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.

Pollock SB, Hu A, Mou Y, Martinko AJ, Julien O, Hornsby M, Ploder L, Adams JJ, Geng H, Müschen M, Sidhu SS, Moffat J, Wells JA. Pollock SB, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2836-2841. doi: 10.1073/pnas.1721899115. Epub 2018 Feb 23. Proc Natl Acad Sci U S A. 2018. PMID: 29476010 Free PMC article.

5

Engineering Improved Antiphosphotyrosine Antibodies Based on an Immunoconvergent Binding Motif.

Mou Y, Zhou XX, Leung K, Martinko AJ, Yu JY, Chen W, Wells JA. Mou Y, et al. Among authors: wells ja. J Am Chem Soc. 2018 Dec 5;140(48):16615-16624. doi: 10.1021/jacs.8b08402. Epub 2018 Nov 19. J Am Chem Soc. 2018. PMID: 30398859

6

Multiomics of azacitidine-treated AML cells reveals variable and convergent targets that remodel the cell-surface proteome.

Leung KK, Nguyen A, Shi T, Tang L, Ni X, Escoubet L, MacBeth KJ, DiMartino J, Wells JA. Leung KK, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):695-700. doi: 10.1073/pnas.1813666116. Epub 2018 Dec 24. Proc Natl Acad Sci U S A. 2019. PMID: 30584089 Free PMC article.

7

Profiling the Surfaceome Identifies Therapeutic Targets for Cells with Hyperactive mTORC1 Signaling.

Wei J, Leung K, Truillet C, Ruggero D, Wells JA, Evans MJ. Wei J, et al. Among authors: wells ja. Mol Cell Proteomics. 2020 Feb;19(2):294-307. doi: 10.1074/mcp.RA119.001785. Epub 2019 Dec 2. Mol Cell Proteomics. 2020. PMID: 31792071 Free PMC article.

8

Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes.

Leung KK, Wilson GM, Kirkemo LL, Riley NM, Coon JJ, Wells JA. Leung KK, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7764-7775. doi: 10.1073/pnas.1917947117. Epub 2020 Mar 23. Proc Natl Acad Sci U S A. 2020. PMID: 32205440 Free PMC article.

9

A SARS-CoV-2 serological assay to determine the presence of blocking antibodies that compete for human ACE2 binding.

Byrnes JR, Zhou XX, Lui I, Elledge SK, Glasgow JE, Lim SA, Loudermilk R, Chiu CY, Wilson MR, Leung KK, Wells JA. Byrnes JR, et al. Among authors: wells ja. medRxiv [Preprint]. 2020 May 29:2020.05.27.20114652. doi: 10.1101/2020.05.27.20114652. medRxiv. 2020. PMID: 32511506 Free PMC article. Updated. Preprint.

10

Engineered ACE2 receptor traps potently neutralize SARS-CoV-2.

Glasgow A, Glasgow J, Limonta D, Solomon P, Lui I, Zhang Y, Nix MA, Rettko NJ, Lim SA, Zha S, Yamin R, Kao K, Rosenberg OS, Ravetch JV, Wiita AP, Leung KK, Zhou XX, Hobman TC, Kortemme T, Wells JA. Glasgow A, et al. Among authors: wells ja. bioRxiv [Preprint]. 2020 Aug 4:2020.07.31.231746. doi: 10.1101/2020.07.31.231746. bioRxiv. 2020. Update in: Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28046-28055. doi: 10.1073/pnas.2016093117. PMID: 32766586 Free PMC article. Updated. Preprint.

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