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Proteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma.
Huang HH, Ferguson ID, Thornton AM, Bastola P, Lam C, Lin YT, Choudhry P, Mariano MC, Marcoulis MD, Teo CF, Malato J, Phojanakong PJ, Martin TG 3rd, Wolf JL, Wong SW, Shah N, Hann B, Brooks AN, Wiita AP. Huang HH, et al. Among authors: hann b. Nat Commun. 2020 Apr 22;11(1):1931. doi: 10.1038/s41467-020-15521-4. Nat Commun. 2020. PMID: 32321912 Free PMC article.
Tumor detection by imaging proteolytic activity.
Darragh MR, Schneider EL, Lou J, Phojanakong PJ, Farady CJ, Marks JD, Hann BC, Craik CS. Darragh MR, et al. Cancer Res. 2010 Feb 15;70(4):1505-12. doi: 10.1158/0008-5472.CAN-09-1640. Epub 2010 Feb 9. Cancer Res. 2010. PMID: 20145119 Free PMC article.
A tumor-suppressing function in the epithelial adhesion protein Trask.
Spassov DS, Wong CH, Harris G, McDonough S, Phojanakong P, Wang D, Hann B, Bazarov AV, Yaswen P, Khanafshar E, Moasser MM. Spassov DS, et al. Among authors: hann b. Oncogene. 2012 Jan 26;31(4):419-31. doi: 10.1038/onc.2011.246. Epub 2011 Jun 27. Oncogene. 2012. PMID: 21706059 Free PMC article.
Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells.
Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita A, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Shuman MA, Wu X, Atkinson JP, Wolf JL, Martin TG, Liu B. Sherbenou DW, et al. Among authors: hann bc. J Clin Invest. 2016 Dec 1;126(12):4640-4653. doi: 10.1172/JCI85856. Epub 2016 Nov 14. J Clin Invest. 2016. PMID: 27841764 Free PMC article.
α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas.
Dodagatta-Marri E, Meyer DS, Reeves MQ, Paniagua R, To MD, Binnewies M, Broz ML, Mori H, Wu D, Adoumie M, Del Rosario R, Li O, Buchmann T, Liang B, Malato J, Arce Vargus F, Sheppard D, Hann BC, Mirza A, Quezada SA, Rosenblum MD, Krummel MF, Balmain A, Akhurst RJ. Dodagatta-Marri E, et al. Among authors: hann bc. J Immunother Cancer. 2019 Mar 4;7(1):62. doi: 10.1186/s40425-018-0493-9. J Immunother Cancer. 2019. PMID: 30832732 Free PMC article.
97 results