Qile M - Search Results

1

LUF7244 plus Dofetilide Rescues Aberrant K_v11.1 Trafficking and Produces Functional I_Kv11.1.

Qile M, Ji Y, Golden TD, Houtman MJC, Romunde F, Fransen D, van Ham WB, IJzerman AP, January CT, Heitman LH, Stary-Weinzinger A, Delisle BP, van der Heyden MAG. Qile M, et al. Mol Pharmacol. 2020 Jun;97(6):355-364. doi: 10.1124/mol.119.118190. Epub 2020 Apr 2. Mol Pharmacol. 2020. PMID: 32241959

2

Glibenclamide and HMR1098 normalize Cantú syndrome-associated gain-of-function currents.

Houtman MJC, Chen X, Qile M, Duran K, van Haaften G, Stary-Weinzinger A, van der Heyden MAG. Houtman MJC, et al. Among authors: qile m. J Cell Mol Med. 2019 Aug;23(8):4962-4969. doi: 10.1111/jcmm.14329. Epub 2019 May 22. J Cell Mol Med. 2019. PMID: 31119887 Free PMC article.

3

LUF7244, an allosteric modulator/activator of K_v 11.1 channels, counteracts dofetilide-induced torsades de pointes arrhythmia in the chronic atrioventricular block dog model.

Qile M, Beekman HDM, Sprenkeler DJ, Houtman MJC, van Ham WB, Stary-Weinzinger A, Beyl S, Hering S, van den Berg DJ, de Lange ECM, Heitman LH, IJzerman AP, Vos MA, van der Heyden MAG. Qile M, et al. Br J Pharmacol. 2019 Oct;176(19):3871-3885. doi: 10.1111/bph.14798. Epub 2019 Aug 30. Br J Pharmacol. 2019. PMID: 31339551 Free PMC article.

4

Class III antiarrhythmic drugs amiodarone and dronedarone impair K_IR 2.1 backward trafficking.

Ji Y, Takanari H, Qile M, Nalos L, Houtman MJC, Romunde FL, Heukers R, van Bergen En Henegouwen PMP, Vos MA, van der Heyden MAG. Ji Y, et al. Among authors: qile m. J Cell Mol Med. 2017 Oct;21(10):2514-2523. doi: 10.1111/jcmm.13172. Epub 2017 Apr 19. J Cell Mol Med. 2017. PMID: 28425222 Free PMC article.

5

Identification of a PEST Sequence in Vertebrate K_IR2.1 That Modifies Rectification.

Qile M, Ji Y, Houtman MJC, Veldhuis M, Romunde F, Kok B, van der Heyden MAG. Qile M, et al. Front Physiol. 2019 Jul 5;10:863. doi: 10.3389/fphys.2019.00863. eCollection 2019. Front Physiol. 2019. PMID: 31333502 Free PMC article.

6

Disease Associated Mutations in K_IR Proteins Linked to Aberrant Inward Rectifier Channel Trafficking.

Zangerl-Plessl EM, Qile M, Bloothooft M, Stary-Weinzinger A, van der Heyden MAG. Zangerl-Plessl EM, et al. Among authors: qile m. Biomolecules. 2019 Oct 25;9(11):650. doi: 10.3390/biom9110650. Biomolecules. 2019. PMID: 31731488 Free PMC article. Review.

7

Drug-likeness of linear pentamidine analogues and their impact on the hERG K⁺ channel - correlation with structural features.

Żołek T, Qile M, Kaźmierczak P, Bloothooft M, van der Heyden MAG, Maciejewska D. Żołek T, et al. Among authors: qile m. RSC Adv. 2019 Dec 2;9(66):38355-38371. doi: 10.1039/c9ra08404e. eCollection 2019 Nov 25. RSC Adv. 2019. PMID: 35540224 Free PMC article.

8

Simvastatin alleviates cardiac fibrosis induced by infarction via up-regulation of TGF-β receptor III expression.

Sun F, Duan W, Zhang Y, Zhang L, Qile M, Liu Z, Qiu F, Zhao D, Lu Y, Chu W. Sun F, et al. Among authors: qile m. Br J Pharmacol. 2015 Aug;172(15):3779-92. doi: 10.1111/bph.13166. Epub 2015 Jun 12. Br J Pharmacol. 2015. PMID: 25884615 Free PMC article.

9

Downregulation of miR-21 is involved in direct actions of ursolic acid on the heart: implications for cardiac fibrosis and hypertrophy.

Dong X, Liu S, Zhang L, Yu S, Huo L, Qile M, Liu L, Yang B, Yu J. Dong X, et al. Among authors: qile m. Cardiovasc Ther. 2015 Aug;33(4):161-7. doi: 10.1111/1755-5922.12125. Cardiovasc Ther. 2015. PMID: 25903305 Free article.

10

Enhanced Placental Mitochondrial Respiration in Tibetan Women at High Altitude.

Liu H, Tenzing N, van Patot MT, Qile M, Ge RL, Wuren T. Liu H, et al. Among authors: qile m. Front Physiol. 2021 Jul 14;12:697022. doi: 10.3389/fphys.2021.697022. eCollection 2021. Front Physiol. 2021. PMID: 34335303 Free PMC article.

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