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The oral protein-kinase C beta inhibitor enzastaurin (LY317615) suppresses signalling through the AKT pathway, inhibits proliferation and induces apoptosis in multiple myeloma cell lines.
Neri A, Marmiroli S, Tassone P, Lombardi L, Nobili L, Verdelli D, Civallero M, Cosenza M, Bertacchini J, Federico M, De Pol A, Deliliers GL, Sacchi S. Neri A, et al. Among authors: tassone p. Leuk Lymphoma. 2008 Jul;49(7):1374-83. doi: 10.1080/10428190802078289. Leuk Lymphoma. 2008. PMID: 18452078
In vivo anti-myeloma activity and modulation of gene expression profile induced by valproic acid, a histone deacetylase inhibitor.
Neri P, Tagliaferri P, Di Martino MT, Calimeri T, Amodio N, Bulotta A, Ventura M, Eramo PO, Viscomi C, Arbitrio M, Rossi M, Caraglia M, Munshi NC, Anderson KC, Tassone P. Neri P, et al. Among authors: tassone p. Br J Haematol. 2008 Nov;143(4):520-31. doi: 10.1111/j.1365-2141.2008.07387.x. Br J Haematol. 2008. PMID: 18986388 Free article.
MicroRNAs in the pathobiology of multiple myeloma.
Lionetti M, Agnelli L, Lombardi L, Tassone P, Neri A. Lionetti M, et al. Among authors: tassone p. Curr Cancer Drug Targets. 2012 Sep;12(7):823-37. doi: 10.2174/156800912802429274. Curr Cancer Drug Targets. 2012. PMID: 22671930 Review.
Canonical and noncanonical Hedgehog pathway in the pathogenesis of multiple myeloma.
Blotta S, Jakubikova J, Calimeri T, Roccaro AM, Amodio N, Azab AK, Foresta U, Mitsiades CS, Rossi M, Todoerti K, Molica S, Morabito F, Neri A, Tagliaferri P, Tassone P, Anderson KC, Munshi NC. Blotta S, et al. Among authors: tassone p. Blood. 2012 Dec 13;120(25):5002-13. doi: 10.1182/blood-2011-07-368142. Epub 2012 Jul 20. Blood. 2012. PMID: 22821765 Free PMC article.
Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: in vitro and in vivo evidence.
Di Martino MT, Leone E, Amodio N, Foresta U, Lionetti M, Pitari MR, Cantafio ME, Gullà A, Conforti F, Morelli E, Tomaino V, Rossi M, Negrini M, Ferrarini M, Caraglia M, Shammas MA, Munshi NC, Anderson KC, Neri A, Tagliaferri P, Tassone P. Di Martino MT, et al. Among authors: tassone p. Clin Cancer Res. 2012 Nov 15;18(22):6260-70. doi: 10.1158/1078-0432.CCR-12-1708. Epub 2012 Oct 3. Clin Cancer Res. 2012. PMID: 23035210 Free PMC article.
DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.
Amodio N, Leotta M, Bellizzi D, Di Martino MT, D'Aquila P, Lionetti M, Fabiani F, Leone E, Gullà AM, Passarino G, Caraglia M, Negrini M, Neri A, Giordano A, Tagliaferri P, Tassone P. Amodio N, et al. Among authors: tassone p. Oncotarget. 2012 Oct;3(10):1246-58. doi: 10.18632/oncotarget.675. Oncotarget. 2012. PMID: 23100393 Free PMC article.
miR-29b negatively regulates human osteoclastic cell differentiation and function: implications for the treatment of multiple myeloma-related bone disease.
Rossi M, Pitari MR, Amodio N, Di Martino MT, Conforti F, Leone E, Botta C, Paolino FM, Del Giudice T, Iuliano E, Caraglia M, Ferrarini M, Giordano A, Tagliaferri P, Tassone P. Rossi M, et al. Among authors: tassone p. J Cell Physiol. 2013 Jul;228(7):1506-15. doi: 10.1002/jcp.24306. J Cell Physiol. 2013. PMID: 23254643
Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth.
Leone E, Morelli E, Di Martino MT, Amodio N, Foresta U, Gullà A, Rossi M, Neri A, Giordano A, Munshi NC, Anderson KC, Tagliaferri P, Tassone P. Leone E, et al. Among authors: tassone p. Clin Cancer Res. 2013 Apr 15;19(8):2096-106. doi: 10.1158/1078-0432.CCR-12-3325. Epub 2013 Feb 27. Clin Cancer Res. 2013. PMID: 23446999 Free PMC article.
In vitro and in vivo anti-tumor activity of miR-221/222 inhibitors in multiple myeloma.
Di Martino MT, Gullà A, Cantafio ME, Lionetti M, Leone E, Amodio N, Guzzi PH, Foresta U, Conforti F, Cannataro M, Neri A, Giordano A, Tagliaferri P, Tassone P. Di Martino MT, et al. Among authors: tassone p. Oncotarget. 2013 Feb;4(2):242-55. doi: 10.18632/oncotarget.820. Oncotarget. 2013. PMID: 23479461 Free PMC article.
388 results