Klima R - Search Results

1

TDP-43 promotes the formation of neuromuscular synapses through the regulation of Disc-large expression in Drosophila skeletal muscles.

Strah N, Romano G, Introna C, Klima R, Marzullo M, Ciapponi L, Megighian A, Nizzardo M, Feiguin F. Strah N, et al. Among authors: klima r. BMC Biol. 2020 Mar 26;18(1):34. doi: 10.1186/s12915-020-00767-7. BMC Biol. 2020. PMID: 32216790 Free PMC article.

2

Chronological requirements of TDP-43 function in synaptic organization and locomotive control.

Romano G, Klima R, Buratti E, Verstreken P, Baralle FE, Feiguin F. Romano G, et al. Among authors: klima r. Neurobiol Dis. 2014 Nov;71:95-109. doi: 10.1016/j.nbd.2014.07.007. Epub 2014 Aug 1. Neurobiol Dis. 2014. PMID: 25088713 Free article.

3

Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms.

Romano G, Appocher C, Scorzeto M, Klima R, Baralle FE, Megighian A, Feiguin F. Romano G, et al. Among authors: klima r. Hum Mol Genet. 2015 Nov 1;24(21):6134-45. doi: 10.1093/hmg/ddv330. Epub 2015 Aug 13. Hum Mol Genet. 2015. PMID: 26276811 Free PMC article.

4

Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses.

Romano G, Holodkov N, Klima R, Grilli F, Guarnaccia C, Nizzardo M, Rizzo F, Garcia R, Feiguin F. Romano G, et al. Among authors: klima r. Sci Rep. 2018 Jan 29;8(1):1809. doi: 10.1038/s41598-018-19802-3. Sci Rep. 2018. PMID: 29379112 Free PMC article.

5

TDP-43 prevents retrotransposon activation in the Drosophila motor system through regulation of Dicer-2 activity.

Romano G, Klima R, Feiguin F. Romano G, et al. Among authors: klima r. BMC Biol. 2020 Jul 3;18(1):82. doi: 10.1186/s12915-020-00816-1. BMC Biol. 2020. PMID: 32620127 Free PMC article.

6

TDP-43 regulates GAD1 mRNA splicing and GABA signaling in Drosophila CNS.

Romano G, Holodkov N, Klima R, Feiguin F. Romano G, et al. Among authors: klima r. Sci Rep. 2021 Sep 21;11(1):18761. doi: 10.1038/s41598-021-98241-z. Sci Rep. 2021. PMID: 34548578 Free PMC article.

7

Depletion of TDP-43 affects Drosophila motoneurons terminal synapsis and locomotive behavior.

Feiguin F, Godena VK, Romano G, D'Ambrogio A, Klima R, Baralle FE. Feiguin F, et al. Among authors: klima r. FEBS Lett. 2009 May 19;583(10):1586-92. doi: 10.1016/j.febslet.2009.04.019. Epub 2009 Apr 19. FEBS Lett. 2009. PMID: 19379745 Free article.

8

TDP-43 regulates Drosophila neuromuscular junctions growth by modulating Futsch/MAP1B levels and synaptic microtubules organization.

Godena VK, Romano G, Romano M, Appocher C, Klima R, Buratti E, Baralle FE, Feiguin F. Godena VK, et al. Among authors: klima r. PLoS One. 2011 Mar 11;6(3):e17808. doi: 10.1371/journal.pone.0017808. PLoS One. 2011. PMID: 21412434 Free PMC article.

9

Evolutionarily conserved heterogeneous nuclear ribonucleoprotein (hnRNP) A/B proteins functionally interact with human and Drosophila TAR DNA-binding protein 43 (TDP-43).

Romano M, Buratti E, Romano G, Klima R, Del Bel Belluz L, Stuani C, Baralle F, Feiguin F. Romano M, et al. Among authors: klima r. J Biol Chem. 2014 Mar 7;289(10):7121-7130. doi: 10.1074/jbc.M114.548859. Epub 2014 Feb 3. J Biol Chem. 2014. PMID: 24492607 Free PMC article.

10

Functional screening in Drosophila reveals the conserved role of REEP1 in promoting stress resistance and preventing the formation of Tau aggregates.

Appocher C, Klima R, Feiguin F. Appocher C, et al. Among authors: klima r. Hum Mol Genet. 2014 Dec 20;23(25):6762-72. doi: 10.1093/hmg/ddu393. Epub 2014 Aug 5. Hum Mol Genet. 2014. PMID: 25096240

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